creators_name: Suryadevara, S creators_name: Kumar, VKV creators_name: Pampanagouda, SKM creators_name: Arjun, R creators_name: Deshmani, V creators_id: sailaja_suryadevara@yahoo.com editors_name: Kakkilaya, Srinivas editors_id: Kakkilaya BS type: journale datestamp: 2016-07-11 15:45:45 lastmod: 2016-07-11 15:45:45 metadata_visibility: show title: Colorectal Cancer Profile in a Tertiary Care Centre, Bangalore, India ispublished: pub subjects: OJHAS full_text_status: public keywords: Early age at presentation; Advanced stage; Lower rectal cancers abstract: Introduction: Colorectal cancers are a common disease of oncological practice. A raising incidence is seen in Asian population. It is one of the cancers where screening and early diagnosis are possible. Very few articles are there about the cancer scenario in India. A study of the disease profile helps in screening, early diagnosis and management of the disease in developing countries. Aim: To study the cancer presentation in our population which can help in developing strategies for better control of disease. Material and Methods: Medical records of 171 patients registered at Kidwai Hospital from 2010 to 2012 were retrospectively reviewed. Data including age at presentation, sex, location of the cancer and stage at presentation were analyzed. Results: The male to female ratio was 1.26:1 in rectal cancer. In colon cancer the ratio was 1:1.3. The mean age at presentation was 47 years in males and 51 years in females in colorectal cancers together. Thirty eight percent of the patients were less than 45 years old. Eighty percent of the cases were rectal cancers. In 71% of rectal cancers the growth was located within 5cm from anal verge (AV). Stage III was the commonest stage of presentation. Abdominoperineal resection (APR) was the commonest surgical procedure done. Inoperability was highest with lower rectal cancer. Conclusion: Younger age at presentation, low lying rectal cancers and advanced stage at presentation were observed in our study group which includes predominantly rural population. Rectal cancers are the most common cancers referred among colorectal cancers. Screening for colorectal cancers and early evaluation of symptomatic cases need to be encouraged. Patients should be educated regarding this. Screening strategies, etiopathogenesis and genetic abnormalities in colorectal cancer patients need to be defined in developing countries. date: 2014-05-15 date_type: published publication: Online Journal of Health and Allied Sciences volume: 13 number: 1 publisher: Kakkilaya BS refereed: TRUE referencetext: 1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin 2011;61:69-90. 2. Kamangar F, Dores GM, Anderson WF. 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Diseases of the Colon and Rectum. 2012;55(8):900-906. citation: Suryadevara, S and Kumar, VKV and Pampanagouda, SKM and Arjun, R and Deshmani, V (2014) Colorectal Cancer Profile in a Tertiary Care Centre, Bangalore, India. [Journal (On-line/Unpaginated)] document_url: http://cogprints.org/9729/1/2014-1-3.pdf