creators_name: Singh, A creators_name: Gangwar, DS creators_id: ajitsingh2409@gmail.com editors_name: Kakkilaya, Srinivas editors_id: Kakkilaya BS type: journale datestamp: 2014-02-25 12:42:05 lastmod: 2014-02-25 12:42:05 metadata_visibility: show title: Autologous Blood versus Corticosteroid Local Injection for Treatment of Lateral Epicondylosis: A Randomized Clinical Trial ispublished: pub subjects: OJHAS full_text_status: public keywords: Autologous blood; Lateral epicondylosis; Steroid injection; Treatment abstract: Objective: The objective of the present single blinded prospective randomized control trial was assessment of efficacy of autologous blood injection versus local steroid injection in treatment of lateral epicondylosis of elbow. Methodology: Using a pre-post experimental design, a total of sixty patients of previously untreated lateral epicondylosis were selected; Group 1 (n=30) was administered single injection of autologous blood and Group 2 (n=30) single local corticosteroid injection. Assessment was done at baseline, 2 weeks, 6 weeks and 12 weeks using PRTEE (Patient Rated Tennis Elbow Evaluation) score. Results: Pre injection parameters showed no difference between groups (chi square test, p > 0.005). Analysis between groups showed significant decrease in steroid group at very short term - 2 weeks (unpaired t test, p < 0.005).There was no difference between groups at 6 weeks. There was a significant improvement in blood group at medium term -12 weeks (unpaired t test, p < 0.05). Conclusion: Both the interventions were effective in reducing pain and improving functional status of patients in short term, but autologous blood was more effective in longer run. date: 2013-08-25 date_type: published publication: Online Journal of Health and Allied Sciences volume: 12 number: 2(11) publisher: Kakkilaya BS refereed: TRUE referencetext: 1. Allander E. Prevalence, incidence, and remission rates of some common rheumatic diseases or syndromes. Scand J Rheumatol. 1974;3:145–53. 2. Dorf ER, Chhabra AB, Golish SR, et al. Effect of elbow position on grip strength in the evaluation of lateral epicondylitis. J Hand Surg [Am]. 2007;32:882–886. 3. Ljung BO, Lieber RL, Fridén J. Wrist extensor muscle pathology in lateral epicondylitis. J Hand Surg Britain. 1999;24:177-183. 4. Tonks JH, Pai SK, Murali SR. Steroid injection therapy is the best conservative treatment for lateral epicondylitis: a prospective randomised controlled trial. Int J Clin Pract. 2007;61:240–246. 5. Vicenzino B, Wright A. Lateral epicondylagia: A review of epidemiology, pathophysiology, etiology and natural history. Phys Ther Rev. 1996;1:23-34. 6. Edwards SG, Calandruccio JH. Autologous blood injections for refractory lateral epicondylitis. The Journal of Hand Surgery. 2003;28A:272–278. 7. Maffulli N, Longo UG, Denaro V. Novel approaches for the management of tendinopathy. J Bone Joint Surg Am. 2010;92:2604–2613. 8. Rompe JD, Overend TJ, MacDermid JC. Validation of the Patient-Rated Tennis Elbow Evaluation Questionnaire. J Hand Ther. 2007;20:3–10; quiz 11. 9. Ashe MC, McCauley T, Khan KM. Tendinopathies in the upper extremity: a paradigm shift. J Hand Ther. 2004;17:329–334. 10. Pattanittum P, Turner T, Green S, Buchbinder R. Non-steroidal anti-inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults. Cochrane Database of Systematic Reviews 2013, Issue 5. Art. No.:CD003686. DOI: 10.1002/14651858.CD003686.pub2. 11. Childress MA, Beutler A. Management of chronic tendon injuries. Am Fam Physician. 2013;87(7):486-490. 12. Harmon K, Drezner J, Rao A. Platelet rich plasma for chronic tendinopathy. Br J Sports Med. 2013 Jun;47(9):x-e2. doi: 10.1136/bjsports-2013-092459.31. 13. Moon YL, Jo SH, Song CH, Park G, Lee HJ, Jang SJ. Autologous Bone Marrow Plasma Injection after Arthroscopic Debridement for Elbow Tendinosis. Ann Acad Med Singapore. 2008;37(7):559-563. 14. Saccomanni B. Corticosteroid injection for tennis elbow or lateral epicondylitis: a review of the literature. Curr Rev Musculoskelet Med. 2010; 15:3(1-4):38-40. 15. Nicola Massy-Westropp, Stuart S, Suzanne C, Andrew P. Autologous Blood Injection and Wrist Immobilisation for Chronic Lateral Epicondylitis. Advances in Orthopedics. 2012; Article ID 387829, 6 pages, doi:10.1155/2012/387829. 16. Molloy T, Wang Y, Murrell G. The roles of growth factors in tendon and ligament healing. Sports Med. 2003;33:381-394. 17. Andia I, Sanchez M, Maffulli N. Tendon healing and platelet-rich plasma therapies. Expert Opin Biol Ther. 2010;10(10):1415–1426. citation: Singh, A and Gangwar, DS (2013) Autologous Blood versus Corticosteroid Local Injection for Treatment of Lateral Epicondylosis: A Randomized Clinical Trial. [Journal (On-line/Unpaginated)] document_url: http://cogprints.org/9159/1/2013-2-11.pdf