--- abstract: 'Multiple sclerosis (MS) is a chronic disease characterized by inflammation, demyelination, gliosis (scarring), and neuronal loss; the course can be relapsing-remitting or progressive. Manifestations of MS vary from a benign illness to a rapidly evolving and incapacitating disease requiring profound lifestyle adjustments. We report a 24 year old female who presented with right internuclear ophthalmoplegia with right lower motor neuron facial nerve palsy which is called eight and half syndrome. The etiology in our patient was multiple sclerosis which was confirmed by radio-imaging studies. Patient improved on pulse therapy of methyl prednisolone and tapering dose of steroids.' altloc: - http://www.ojhas.org/issue44/2012-4-15.html chapter: ~ commentary: ~ commref: ~ confdates: ~ conference: ~ confloc: ~ contact_email: ~ creators_id: - nmsbabu18@yahoo.com - ~ - ~ - ~ - ~ creators_name: - family: Raina given: R honourific: '' lineage: '' - family: Kaushik given: M honourific: '' lineage: '' - family: Mahajan given: SK honourific: '' lineage: '' - family: Raghav given: S honourific: '' lineage: '' - family: Sharathbabu given: NM honourific: '' lineage: '' date: 2013-01-25 date_type: published datestamp: 2013-05-04 23:09:42 department: ~ dir: disk0/00/00/89/44 edit_lock_since: ~ edit_lock_until: 0 edit_lock_user: ~ editors_id: - Kakkilaya BS editors_name: - family: Kakkilaya given: Srinivas honourific: Dr lineage: '' eprint_status: archive eprintid: 8944 fileinfo: /style/images/fileicons/application_pdf.png;/8944/1/2012-4-15.pdf full_text_status: public importid: ~ institution: ~ isbn: ~ ispublished: pub issn: ~ item_issues_comment: [] item_issues_count: ~ item_issues_description: [] item_issues_id: [] item_issues_reported_by: [] item_issues_resolved_by: [] item_issues_status: [] item_issues_timestamp: [] item_issues_type: [] keywords: Eight and half syndrome; Multiple sclerosis; Fifteen and half syndrome. lastmod: 2013-05-04 23:09:42 latitude: ~ longitude: ~ metadata_visibility: show note: ~ number: 4(15) pagerange: ~ pubdom: TRUE publication: Online Journal of Health and Allied Sciences publisher: Kakkilaya BS refereed: TRUE referencetext: "1.\tHauser SL, Goodin DS. Multiple Sclerosis and other demyelinating diseases. Harrison’s principles of internal medicine 18th edition New York: McGraw Hill; 2012. p. 3395-3409.\r\n2.\tEggenberg E. Eight-and-a-half syndrome. J Neuroophthalmol 1998;18:114-116.\r\n3.\tWolfe GI, Galetta SL, Mollman JE. Spontaneous remission of papilledema and sixth nerve palsy in acute lymphoblastic leukemia. J Neuro-Ophthalmol 1994;14:91-94.\r\n4.\tBae JS, Song HK. One-and-a-half syndrome with facial diplegia: the 15 1/2 syndrome? J Clin Neuroophthalmol 2005;25:52-53.\r\n5.\tAnderson CA, Sanberg E, Filley CM, et al. One and one-half syndrome with supranuclear facial weakness. Arch Neurol 1999;56:1509-1511.\r\n6.\tKim JS. Internuclear ophthalmoplegia as an isolated or predominant symptom of brainstem infarction. Neurology 2004;62:1491-1496.\r\n7.\tOhta K, Gotoh F, Fukuuchi Y, et al. Midpontine tegmentum infarction with one-and-a-half syndrome� demonstrated by magnetic resonance imaging. Keio J Med 1994;43:164-165.\r\n8.\tWall M, Wray SH. The one-and-a-half syndrome. A unilateral disorder of the pontine tegmentum: a study of 20 cases and review of the literature. Neurology 1983;33:971-980." relation_type: [] relation_uri: [] reportno: ~ rev_number: 9 series: ~ source: ~ status_changed: 2013-05-04 23:09:42 subjects: - OJHAS succeeds: ~ suggestions: ~ sword_depositor: ~ sword_slug: ~ thesistype: ~ title: A Case of Multiple Sclerosis Presenting as Eight and Half Syndrome. type: journale userid: 4338 volume: 11