creators_name: Jagtap, SV creators_name: Nikumbh, DB creators_name: Khirsagar, AY creators_name: Jagtap, SS creators_name: S, Khan creators_id: drsvjagtap@gmail.com editors_name: Kakkilaya, Srinivas editors_id: Kakkilaya BS type: journale datestamp: 2013-05-04 23:05:08 lastmod: 2013-05-04 23:05:08 metadata_visibility: show title: Primary Signet-Ring Carcinoma (Linitus Plastica) of the Colorectum presenting as Subacute Intestinal Obstruction ispublished: pub subjects: OJHAS full_text_status: public keywords: Signet ring cell carcinoma; Colorectal neoplasm; Linitus plastica abstract: Primary Signet-ring cell carcinoma (Linitus Plastica) of the colon and rectum is a rare form of adenocarcinoma of the large intestine and has been reported to have an extremely poor prognosis. We report a case of Primary Signet-ring cell carcinoma of the colorectum in a thirty one year old man presented in Surgical OPD of our hospital with chief complaints of persistent pain in abdomen and vomiting since two days. Since the prognosis of primary signet ring cell carcinoma (SRCC) is extremely poor (in view of more malignant behavior than ordinary colorectal carcinoma), early diagnosis and aggressive treatment strategy are necessary. date: 2012-04-15 date_type: published publication: Online Journal of Health and Allied Sciences volume: 11 number: 1(14) publisher: BS Kakkilaya refereed: TRUE referencetext: 1. Giacchero A, Aste H, Barachhini P, Conio M, Fulcheri E, Laperto G, Tanzi R. Primary signet-ring cell carcinoma of large bowel. Report of nine cases. Cancer. 1985; 56(11):2723-2726. 2. Almagro UA. Primary signet-ring cell carcinoma of the colon. Cancer. 1983;52:1453-1457. 3. Tung SY, Wu CS, Chen PC. Primary signet-ring cell carcinoma of colorectum :an age and sex matched controlled study. Am J Gastroenterol. 1996;91:2195-2199. 4. Sim HL, Tan KY, Poon PL, Cheng A. Primary rectal signet-ring cell carcinoma with peritoneal dissemination and gastric secondaries. World J Gastroenterol. 2008;14(3):2118-2120. 5. Maeharn Y, Sakaguchi Y, Moriguchi S et al. Signet ring carcinoma of the stomach. Cancer. 1992;69:1645-1650. 6. Tendon M, Sostek M, Klein MA. Focus of signet ring-cell carcinoma in an adenoma of the sigmoid colon. Arch Pathol Lab Med. 1999;123:957-959. 7. Messerini L, Palomba A, Zampi G. Primary signet-ring cell carcinoma of the colon and rectum. Dis Colon Rectum. 1995;38:1189-1192. 8. Laufman H, Safir O. Primary linitus plastica type of carcinoma of the colon. AMA Arch Surg. 1951;62:79-91. 9. Nakahara H, Ishikawa T, Itubashi M, Hirota T. Diffusely infiltrating colorectal carcinoma of linitus plastic and lymphangiosis type. Cancer. 1992;69:901-906. 10. Goldstein NS, Long A, Kuan SF, Hart J. Colon signet ring-cell adenocarcinoma: immunohistochemical characterization and comparison with gastric and typical colon adenocarcinomas. Appl Immunohistochem Mol Morphol. 2008;8:183-188. 11. Tot T. The role of cytokeratins 20 and 7 and estrogen receptor analysis in separation of metastatic lobular carcinoma of the breast and metastatic signet-ring cell carcinoma of the gastrointestinal tract. APMIS. 2000;108:467-472. 12. Varadhachary GR, Abbnizzese JL, Lenzi R. Diagnostic strategies for unknown primary cancer. Cancer. 2004;100:1776-1785. citation: Jagtap, SV and Nikumbh, DB and Khirsagar, AY and Jagtap, SS and S, Khan (2012) Primary Signet-Ring Carcinoma (Linitus Plastica) of the Colorectum presenting as Subacute Intestinal Obstruction. [Journal (On-line/Unpaginated)] document_url: http://cogprints.org/8879/1/2012-1-14.pdf