--- abstract: 'Background: Transfusion of blood and blood products is a life saving intervention and benefits innumerous patients worldwide. At the same time it could be an ominous mode of infection transmission to recipients. In 15 percent of total patients infected with HIV, blood transfusion has been the responsible mechanism of transmission. Methods: In this study, we aimed to access the prevalence and trend of HIV, HBV, HCV and Syphilis over the last 3½ years (January 2008 to June 2011) among the blood donors who came to donate blood at Blood Bank, P.D.U. Medical College & Hospital, Rajkot as well as in various blood donation camps organized by the same blood bank. Results: From the total of 30,178 blood donors, 711 (2.35%) had serological evidence of infection with at least one pathogen, either of HIV, HBV, HCV or Syphilis. These included 131 (0.43%) with HIV, 293 (0.97%) with HBV, 124 (0.41%) with HCV and 94 (0.31%) with Syphilis. Moreover, significantly declining trends of HIV, HBV and Syphilis was observed over the study period. Conclusion: A substantial percentage of blood donors harbor HIV, HBV, HCV and Syphilis infections. Strict selection of blood donors and comprehensive screening of donors’ blood using standard methods are highly recommended to ensure the safety of blood for recipient.' altloc: - http://www.ojhas.org/issue41/2012-1-5.htm chapter: ~ commentary: ~ commref: ~ confdates: ~ conference: ~ confloc: ~ contact_email: ~ creators_id: - ~ - ~ - path.pdumc@gmail.com creators_name: - family: Dhruva given: GA honourific: '' lineage: '' - family: Agravat given: AH honourific: '' lineage: '' - family: Pujara given: KM honourific: '' lineage: '' date: 2012-04-15 date_type: published datestamp: 2013-05-04 23:04:35 department: ~ dir: disk0/00/00/88/70 edit_lock_since: ~ edit_lock_until: 0 edit_lock_user: ~ editors_id: - Kakkilaya BS editors_name: - family: Kakkilaya given: Srinivas honourific: Dr lineage: '' eprint_status: archive eprintid: 8870 fileinfo: /style/images/fileicons/application_pdf.png;/8870/1/2012-1-5.pdf full_text_status: public importid: ~ institution: ~ isbn: ~ ispublished: pub issn: ~ item_issues_comment: [] item_issues_count: ~ item_issues_description: [] item_issues_id: [] item_issues_reported_by: [] item_issues_resolved_by: [] item_issues_status: [] item_issues_timestamp: [] item_issues_type: [] keywords: Blood donors; HIV; HBV; HCV; Syphilis; Transfusion transmissible infection (TTI). lastmod: 2013-05-04 23:04:35 latitude: ~ longitude: ~ metadata_visibility: show note: ~ number: 1(5) pagerange: ~ pubdom: TRUE publication: Online Journal of Health and Allied Sciences publisher: BS Kakkilaya refereed: TRUE referencetext: "1.\tDolly R, Annie S, Thaiyanayaki P, Babu George P, Hohn Jacob T. Increasing prevalence of HIV antibody among blood donors monitored over 9 years in blood bank. Indian J Med Res 1998;108:42-44.\r\n2.\tGarg S, Mathur DR, Garg DK. Comparison of seropositivity of HIV, HBV, HCV and Syphilis in replacement and voluntary blood donors in western India. Indian J Pathol Microbiol 2001;44:409-412.\r\n3.\tWard JW, Deppe DA, Samson S, Perkins H, Holland P, Fernando L, et al. Risk of HIV infection from blood donors who later developed the acquired immunodeficiency syndrome. Ann Intern Med 1987;106:61-62.\r\n4.\tLal S. Monthly update on HIV infection in India. Center AIDS Res Contr. 1993;6:133-134.\r\n5.\tKaur P, Basu S. Transfusion transmitted infections: Existing and emerging pathogens. Journal of Post Graduate Medicine. 2005;51:(2):146-151.\r\n6.\tGlynn SA, Kleinman SH, Wright DJ, Busch MP. For the NHLBI Retrovirus Epidemiology Donor study: International application of the incidence rate/window period model. Transfusion 2002;42:966-972.\r\n7.\tJackson BR, Busch MP, Stramer SL, AuBuchon JP. The cost-effectiveness of NAT for HIV, HCV and HBV in whole-blood donations. Transfusion 2003;43:721-729." relation_type: [] relation_uri: [] reportno: ~ rev_number: 9 series: ~ source: ~ status_changed: 2013-05-04 23:04:35 subjects: - OJHAS succeeds: ~ suggestions: ~ sword_depositor: ~ sword_slug: ~ thesistype: ~ title: 'Seroprevalence of HIV, HBV, HCV and Syphilis in Blood Donors in Saurashtra Region of Gujarat: Declining Trends Over a Period of 3½ Years' type: journale userid: 4338 volume: 11