--- abstract: "The subthalamic nucleus (STN), which receives excitatory inputs from the cortex and has direct connections with the inhibitory pathways\r\nof the basal ganglia, is well positioned to efficiently mediate action selection. Here, we use microelectrode recordings captured during\r\ndeep brain stimulation surgery as participants engage in a decision task to examine the role of the human STN in action selection. We\r\ndemonstrate that spiking activity in the STN increases when participants engage in a decision and that the level of spiking activity\r\nincreases with the degree of decision conflict. These data implicate the STN as an important mediator of action selection during decision\r\nprocesses.\r\n" altloc: [] chapter: ~ commentary: ~ commref: ~ confdates: ~ conference: ~ confloc: ~ contact_email: ~ creators_id: [] creators_name: - family: Zaghloul given: K. A. honourific: '' lineage: '' - family: Weidemann given: Christoph T. honourific: '' lineage: '' - family: Lega given: B. C. honourific: '' lineage: '' - family: Jaggi given: J. L. honourific: '' lineage: '' - family: Baltuch given: G. H. honourific: '' lineage: '' - family: Kahana given: M. J. honourific: '' lineage: '' date: 2012 date_type: published datestamp: 2012-11-09 20:00:07 department: ~ dir: disk0/00/00/87/18 edit_lock_since: ~ edit_lock_until: 0 edit_lock_user: ~ editors_id: [] editors_name: [] eprint_status: archive eprintid: 8718 fileinfo: /8718/1.hassmallThumbnailVersion/ZaghloulEtAl2012.pdf;/8718/1/ZaghloulEtAl2012.pdf full_text_status: public importid: ~ institution: ~ isbn: ~ ispublished: pub issn: ~ item_issues_comment: [] item_issues_count: ~ item_issues_description: [] item_issues_id: [] item_issues_reported_by: [] item_issues_resolved_by: [] item_issues_status: [] item_issues_timestamp: [] item_issues_type: [] keywords: ~ lastmod: 2013-02-18 15:13:12 latitude: ~ longitude: ~ metadata_visibility: show note: ~ number: ~ pagerange: 2453-2460 pubdom: TRUE publication: The Journal of Neuroscience publisher: ~ refereed: TRUE referencetext: ~ relation_type: [] relation_uri: [] reportno: ~ rev_number: 13 series: ~ source: ~ status_changed: 2012-11-09 20:00:07 subjects: - behav-neuro-sci - cog-psy - comp-neuro-sci succeeds: ~ suggestions: ~ sword_depositor: ~ sword_slug: ~ thesistype: ~ title: Neuronal Activity in the Human Subthalamic Nucleus Encodes Decision Conflict during Action Selection type: journalp userid: 6246 volume: 32