<> "The repository administrator has not yet configured an RDF license."^^ . <> . . "Dopaminergic Regulation of Neuronal Circuits in Prefrontal Cortex"^^ . "Neuromodulators, like dopamine, have considerable influence on the\r\nprocessing capabilities of neural networks. \r\nThis has for instance been shown in the working memory functions\r\nof prefrontal cortex, which may be regulated by altering the\r\ndopamine level. Experimental work provides evidence on the biochemical\r\nand electrophysiological actions of dopamine receptors, but there are few \r\ntheories concerning their significance for computational properties \r\n(ServanPrintzCohen90,Hasselmo94).\r\nWe point to experimental data on neuromodulatory regulation of \r\ntemporal properties of excitatory neurons and depolarization of inhibitory \r\nneurons, and suggest computational models employing these effects.\r\nChanges in membrane potential may be modelled by the firing threshold,\r\nand temporal properties by a parameterization of neuronal responsiveness \r\naccording to the preceding spike interval.\r\nWe apply these concepts to two examples using spiking neural networks.\r\nIn the first case, there is a change in the input synchronization of\r\nneuronal groups, which leads to\r\nchanges in the formation of synchronized neuronal ensembles.\r\nIn the second case, the threshold\r\nof interneurons influences lateral inhibition, and the switch from a \r\nwinner-take-all network to a parallel feedforward mode of processing.\r\nBoth concepts are interesting for the modeling of cognitive functions and may\r\nhave explanatory power for behavioral changes associated with dopamine \r\nregulation."^^ . "2001-08-10" . . . "accepted at Neural Networks in 2001"^^ . . . . . . . . "Gabriele"^^ . "Scheler"^^ . "Gabriele Scheler"^^ . . . . . . "Dopaminergic Regulation of Neuronal Circuits in Prefrontal Cortex (PDF)"^^ . . . . . "neural-networks-2012.pdf"^^ . . . "Dopaminergic Regulation of Neuronal Circuits in Prefrontal Cortex (Image (PNG))"^^ . . . . . . "lightbox.jpg"^^ . . . "Dopaminergic Regulation of Neuronal Circuits in Prefrontal Cortex (Image (PNG))"^^ . . . . . . "preview.jpg"^^ . . . "Dopaminergic Regulation of Neuronal Circuits in Prefrontal Cortex (Image (PNG))"^^ . . . . . . "medium.jpg"^^ . . . "Dopaminergic Regulation of Neuronal Circuits in Prefrontal Cortex (Image (PNG))"^^ . . . . . . "small.jpg"^^ . . . "Dopaminergic Regulation of Neuronal Circuits in Prefrontal Cortex (Indexer Terms)"^^ . . . . . . "indexcodes.txt"^^ . . "HTML Summary of #8082 \n\nDopaminergic Regulation of Neuronal Circuits in Prefrontal Cortex\n\n" . "text/html" . . . "Cognitive Psychology" . . . "Computational Neuroscience" . . . "Neural Nets" . . . "Neural Modelling" . . . "Neuropsychology" . . . "Neuropsychiatry" . .