creators_name: Girish, PN creators_name: Shetty, NJ creators_name: Shetty, VH creators_name: Vaz, GF creators_id: pattegiri@yahoo.co.in editors_name: Kakkilaya, Srinivas editors_id: BS Kakkilaya type: journale datestamp: 2012-11-09 17:37:18 lastmod: 2012-11-09 17:37:18 metadata_visibility: show title: Study of the Clinical Patterns in Varicella in a Tertiary Hospital at Coastal Karnataka ispublished: pub subjects: OJHAS full_text_status: public keywords: Varicella; Cutaneous manifestations; Vaccination abstract: Context: There are very few studies regarding the clinical patterns and manifestations of a very common viral infection, Varicella, especially from south India. Aims: To study the cutaneous manifestation of Varicella with an emphasis on vaccination status. Settings and Design: Cross sectional study. Methods and Material: A total of 118 patients attending the Dermatology OPD of a private medical college in coastal Karnataka with cutaneous manifestations of varicella were enrolled. Study period was from January 2010 to December 2010. Statistical analysis used: Data was analysed using SPSS version 11.5. Various frequency distribution tables, diagrams and chi square test were used to describe and analyse the data. Results: Majority of the patients were males (62.7%) and 21-30 years was the most common age group involved. There were 74 students, out of which eight were in the preschool group aged between 3-4 years. Most of the patients visited the hospital on the second day after onset of the symptoms. 108(91.5%) patients complained about the presence of various prodromal symptoms. Scalp was the most common (39.8%) site of onset of the rash. Itching was experienced by 76(64.4%) patients. Peak number of cases (35.6%) was seen in the month of January. The cutaneous rash was most commonly (57.7%) distributed over face, scalp, trunk, upper and lower limbs, with predominantly central distribution. Soft palate was the most common site (87%) involved in the oral cavity. Conclusions: A wide variety of combination symptoms with classical cutaneous polymorphic vesicular rash and oral lesions was seen. date: 2011-11-15 date_type: published publication: Online Journal of Health and Allied Sciences volume: 10 number: 3 publisher: BS Kakkilaya refereed: TRUE referencetext: 1. Heininger U and Seward JF. Varicella. Lancet 2006;368:1365-1376 2. McCrary ML, Severson J, Tyring SK. Varicella zoster virus. J Am Acad Dermatol 1999;41:1-14 3. Liyange NP, Fernado S, Malavige GN, Mallikahewa R, Sivayogan S, Jiffry MT et al. Seroprevalence of varicella zoster virus infections in Colombo District, Sri Lanka. Indian J Med Sci 2007;61:128-134 4. Lokeshwar MR, Agarwal A, Subbarao SD, Chakraborty MS, Ram Prasad AV, Weil J et al. Age related seroprevalence of antibodies to varicella in India. Indian Pediatr 2000;37:714-719 5. Venkitaraman AR, John TJ. The epidemiology of varicella in staff and students of a hospital in the tropics. Int J Epidemiol 1984;13:502-505 6. Garnett GP, Cox MJ, Bundy DA, Didier JM, St Catharine J. The age of infection with varicella-zoster virus in St Lucia, West Indies. Epidemiol Infect 1993;110:361-372 7. Mandal BK, Mukherjee PP, Murphy C, Mukherjee R, Naik T. Adult susceptibility to varicella in the tropics is a rural phenomenon due to the lack of previous exposure. J Infect Dis 1998;178:52-54 8. Chen TM, George S, Woodruff CA, Hsu S. Clinical manifestations of varicella-zoster virus infection. Dermatol Clin 2002;20:267-282 9. Lee BW. Review of varicella zoster seroepidemiology in India and Southeast Asia. Trop Med Int Health 1998;3:886-890 10. Paryani SG, Arvin AM. Intrauterine infection with varicella-zoster virus after maternal varicella. N Engl J Med 1986;314:1542-1546 11. Chaves SS, Zhang J, Civen R, Watson BM, Carbajal T, Perella D et al. Varicella disease among vaccinated persons: clinical and epidemiological characteristics, 1997-2005. J Infect Dis 2008;197:127-131 12. Lopez AS, Guris D, Zimmerman L, Gladden L, Moore T, Haselow DT et al. One dose of varicella vaccine does not prevent school outbreaks- is it time for a second dose? Pediatrics 2006;117:1070-1077 13. Agampodi SB, Dharmaratne SD, Thevanesam V, Dassanayake S, Kumarihamy P, Ratnayake A. Incidence and effects of Varicella Zoster Virus infection on academic activities of medical undergraduates- a five-year follow-up study from Sri Lanka. BMC Infect Dis 2010;10:117 14. Welgama U, Wickramasinghe C, Perera J. Varicella-zoster virus infection in the Infectious Diseases Hospital, Sri Lanka. Ceylon Med J 2003;48:119-121 15. Fairley CK, Miller E. Varicella-zoster virus epidemiology- a changing scene? J Infect Dis 1996;174:314-319 16. Straus SE, Oxman MN, Schmader KE. Varicella and Herpes Zoster. In Wolf K, Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ editors. Fitzpatrick’s Dermatology in General Medicine. 7th edition. New York: McGraw Hill; 2008. p.1885-1898. citation: Girish, PN and Shetty, NJ and Shetty, VH and Vaz, GF (2011) Study of the Clinical Patterns in Varicella in a Tertiary Hospital at Coastal Karnataka. [Journal (On-line/Unpaginated)] document_url: http://cogprints.org/8013/1/2011-3-6.pdf