creators_name: Pawar, SK creators_name: Ghorpade, MV creators_name: Aundhkar, S creators_id: drskpawar@gmail.com editors_name: Kakkilaya, Srinivas editors_id: BS Kakkilaya type: journale datestamp: 2012-11-09 17:37:19 lastmod: 2012-11-09 17:37:19 metadata_visibility: show title: Culture Positive Brucella Endocarditis in a Case of Baloon Mitral Valvotomy ispublished: pub subjects: OJHAS full_text_status: public keywords: Brucella; Endocarditis; Mitral valve abstract: Brucella endocarditis is a rare condition which occurs as a focal complication in chronic brucellosis cases. We report a rare brucella endocarditis case in a RVHD patient. A 26 years old male was admitted with fever on off for almost one year. The blood culture yielded growth of Brucella melitensis after ten days of incubation. Isolated colonies were reconfirmed as Brucella species by PCR study. Patient’s serum tested positive for brucella slide agglutination test and STAT titer was 640IU. Echocardiography showed vegetation on mitral valve. Patient was treated with both medical and surgical intervention. After chemotherapy, patient’s blood culture was sterile, slide agglutination & STAT (40IU) were negative. Repeat echocardiography showed no fresh vegetation. Considering high mortality rate (80%) in Brucella endocarditis, it is very important for clinicians to suspect it. Prompt antibiotic therapy and surgical intervention is life saving in fatal cases. date: 2011-11-15 date_type: published publication: Online Journal of Health and Allied Sciences volume: 10 number: 3 publisher: BS Kakkilaya refereed: TRUE referencetext: 1. Zisis C, Argyriou M, Kokotsakis I, et al. Brucella Endocarditis. Presentation of two cases and literature review. Hellenic J Cardiol. 2002;43:174-177. 2. Purwar S, Metgud SC, Darshan A et al. Infective Endocarditis Due to Brucella. Indian J Med Microbiol. 2006;24(4):286 -288. 3. Mantur BG, Amarnath SK. Brucellosis in India – a review. J Biosci. 2008;33(4):539-547. 4. Hadjinikolau L, Triposkiadis F, Zaris M et al. Successful management of Brucella melitensis endocarditis with combined medical and surgical approach. Eur J Cardiothorac Surg. 2001;19:806–810. 5. Je HG, Song H. Brucella Endocarditis in a Non–Endemic Country–First Reported case in East Asia. Circ J. 2008;72:500–501. citation: Pawar, SK and Ghorpade, MV and Aundhkar, S (2011) Culture Positive Brucella Endocarditis in a Case of Baloon Mitral Valvotomy. [Journal (On-line/Unpaginated)] document_url: http://cogprints.org/8009/1/2011-3-12.pdf