?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=On+the+origins+of+aperiodicities+in+sensory+neuron+entrainment&rft.creator=Read%2C+Heather+L&rft.creator=Siegel%2C+Ralph+M&rft.subject=Neurology&rft.subject=Neurophysiology&rft.description=Aperiodic+entrainment+to+rhythmic+sensory+input+was+obtained+with+either+a+single+neuron+or+an+excitatory+network+model%2C+without+addition+of+a+stochastic+or+%22noisy%22+element.+The+entrainment+properties+of+primary+sensory+neurons+were+well+captured+by+the+dynamics+of+the+Hodgkin-Huxley+ordinary+differential+equations+with+a+quiescent+resting+state+or+threshold+for+spike+output.+The+frequency-amplitude+parameter+space+was+compressed+and+aperiodic+regimes+were+small+in+comparison+to+those+of+periodically+activated+pacemaker+like+neurons.+Transitions+between+phase-locked+and+aperiodic+entrainment+patterns+were+predictable+and+determined+by+the+equation+dynamics%3B+supporting+the+contention+that+some+aperiodicities+observed+%24%7Bin%7D%24+%24%7Bsitu%7D%24+arise+from+the+inherent+membrane+properties+of+neurons.+When+the+rhythmically+activated+neuron+was+embedded+in+an+excitatory+network+of+Hodgkin-Huxley+neurons+with+heterogeneous+synaptic+delays%2C+aperiodic+entrainment+patterns+were+more+frequently+encountered+and+these+were+associated+with+asynchronous+output+from+the+network.+Embedding+the+rhythmically+activated+neuron+in+a+network+with+synaptic+delays%2C+greatly+reduced+the+range+of+entrained+spike+frequencies.+Other+biological+mechanisms+of+modifying+the+entrainment+properties+and+promoting+aperiodic+entrainment+are+discussed.&rft.date=1996&rft.type=Journal+(Paginated)&rft.type=NonPeerReviewed&rft.format=text%2Fhtml&rft.identifier=http%3A%2F%2Fcogprints.org%2F8%2F1%2Fneurosci96.html&rft.identifier=++Read%2C+Heather+L+and+Siegel%2C+Ralph+M++(1996)+On+the+origins+of+aperiodicities+in+sensory+neuron+entrainment.++%5BJournal+(Paginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F8%2F