creators_name: Pailoor, K creators_name: Swethadri, GK creators_name: Jayaprakash, C creators_name: Fernandes, H creators_id: dockirana@yahoo.co.uk editors_name: Kakkilaya, Srinivas editors_id: BS Kakkilaya type: journale datestamp: 2012-11-09 17:37:20 lastmod: 2012-11-09 17:37:20 metadata_visibility: show title: B-cell Prolymphocytic Leukemia in a Young Male ispublished: pub subjects: OJHAS full_text_status: public keywords: B-PLL; Prolymphocyte; Massive splenomegaly; Immunophenotyping abstract: B-cell prolymphocytic leukemia [B-PLL] is a neoplasm of B prolymphocytes affecting the peripheral blood, bone marrow and spleen. The principal disease characteristics are massive splenomegaly with absent or minimal peripheral lymphadenopathy and a rapidly rising lymphocyte count. Here, we report a case of B-PLL in a 42 year old male who had come for routine health check up. date: 2011-07-30 date_type: published publication: Online Journal of Health and Allied Sciences volume: 10 number: 2 publisher: BS Kakkilaya refereed: TRUE referencetext: 1. Campo E, Catovsky D, Montserrat E, Muller-Hermelink HK, Harris NL, Stein H. B-cell prolymphocytic leukemia. In: WHO Classification of tumors of hematopoietic and lymphoid tissues. 4th edn. Lyon 2008. Pg.183-184. 2. Naseem S, Gupta R, Kashyap R, Nityanand S. T-cell prolymphocytic leukemia: a report of two cases with review of literature. Indian J. Hematol Blood Transfus2008;24(4):178-181. 3. Katayama I, Aiba M, Pechet L, Sullivan J, Robert P, Humphreys RE. B- lineage prolymphocytic leukemia as a distinct clinicopathologic entity. Am J Pathol1980;99:399-412. 4. Kar R, Kumar R, Tyagi S. De-novo CD5+ B-prolymphocytic leukemia presenting at younger age with favourable outcome. Turk J Hematol 2008;25:149-151. 5. Schlette E, Bueso-Ramos C, Giles F, Glassman A, Hayes K, Medeiros J. Mature B-cell Leukemias with more than 55% prolymphocytes – A heterogenous group that includes an unusual variant of Mantle cell lymphoma. Am J Clin Pathol 2001;115:571-581. 6. Merchant S, Schlette E, Sanger W, Lai R, Medeiros J. Mature B-cell Leukemias with more than 55% prolymphocytes – Report of 2 cases with Burkitt Lymphoma – type chromosomal translocations involving c-myc. Arch Pathol Lab Med 2003;127:305-309. 7. Bearman RM, Pangalis GA, Rappaport H. Prolymphocytic Leukemia – Clinical, Histopathological and Cytochemical Observations. Cancer 1978;42:2360-2372. 8. Nayak KS, Narayanan S, Naik R, Khadilkar UN. Prolymphocytic Leukemia – report of three cases. Indian J Pathol Microbiol 2003;46(3):459-461. citation: Pailoor, K and Swethadri, GK and Jayaprakash, C and Fernandes, H (2011) B-cell Prolymphocytic Leukemia in a Young Male. [Journal (On-line/Unpaginated)] document_url: http://cogprints.org/7987/1/2011-2-25.pdf