--- abstract: 'The present study was undertaken in sixty patients of viral hepatitis of both sexes ranging 20 to 60 yrs. of age to compare serum levels or 5’Nucleotidase, Alkaline phosphatase, aspartate aminotransferase, and alanine aminotransferase & serum bilirubin. Forty of clinically healthy subjects were taken as control group. These were patient’s attendants without any evidence of liver disease so as to equlibriate the socioeconomic status and age. The study group patients were either admitted to Rajindra Hospital, Patiala, or attending the OPD. A detailed clinical examination was carried out in all as per plan mentioned in materials & methods. Diagnosis of these patients was based on clinical findings. Endeavour was to find out a single enzyme marker which is most specific and sensitive parameter out of all above. It was later concluded that value of 5’ NT was highly significant as compared to ALP. A positive correlation was observed between AST, ALT & serum bilirubin level. But 5’ NT showed no correlation with aminotransferases.' altloc: [] chapter: ~ commentary: ~ commref: ~ confdates: ~ conference: ~ confloc: ~ contact_email: ~ creators_id: [] creators_name: - family: Anil Batta given: 'Int J Cur Bio Med Sci. ' honourific: '' lineage: '' date: 2011-04-30 date_type: published datestamp: 2011-05-02 15:52:32 department: ~ dir: disk0/00/00/73/20 edit_lock_since: ~ edit_lock_until: 0 edit_lock_user: ~ editors_id: [] editors_name: [] eprint_status: archive eprintid: 7320 fileinfo: /style/images/fileicons/application_pdf.png;/7320/1/Viral_Hepatitis_And_Enzyme_Study.pdf full_text_status: public importid: ~ institution: ~ isbn: ~ ispublished: pub issn: ~ item_issues_comment: [] item_issues_count: 0 item_issues_description: [] item_issues_id: [] item_issues_reported_by: [] item_issues_resolved_by: [] item_issues_status: [] item_issues_timestamp: [] item_issues_type: [] keywords: ' Jaundice, enzyme assay,correlation,hepatocellular damage, cholestasis ,viruses A B C D E' lastmod: 2011-05-02 15:52:32 latitude: ~ longitude: ~ metadata_visibility: show note: ~ number: 2 pagerange: 41-43 pubdom: TRUE publication: 'Int J Cur Bio Med Sci. ' publisher: CurrentSciDirect Publications refereed: TRUE referencetext: "[1]\tBarnes P, Powell-Griner E, McFann K, Nahin R. CDC advance data report #343. Complementary and alternative medicine use among adults: United States, 2002. May 27, 2004. \r\n[2]\tVogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract 1999;49:823-828. \r\n[3]\tHarkey MR, Henderson GL, Gershwin ME, Stern JS, Hackman RM. Variability in commercial ginseng products: an analysis of 25 preparations. Am J Clin Nutr 2001;73:1101-1106. \r\n[4]\tChitturi S, Farrell GC. Herbal hepatotoxicity: an expanding but poorly defined problem. J Gastroenterol Hepatol 2000;15:1093-1099. \r\n[5]\tRabe C, Musch A, Schirmacher P, Kruis W, Hoffmann R. Acute hepatitis induced by an Aloe vera preparation: a case report. World J Gastroenterol 2005;11:303-304\r\n[6]\tKanat O, Ozat A, Ataergin S. Aloe vera-induced toxic hepatitis in a healthy young man. Eur J Intern Med 2006;17:589-590. \r\n[7]\tAlvarez F, Berg PA, Bianchi FB, et al. International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 1999;31:929-938. \r\n[8]\tAndrade RJ, Lucena MI, Fernández MC, et al. Drug-induced liver injury: an analysis of 461 incidences submitted to the Spanish registry over a 10-year period. Gastroenterology 2005;129:512-21\r\n[9]\tNavarro VJ, Senior JR. Drug-related hepatotoxicity. N Engl J Med 2006;354:731-9. Naranjo CA, Busto U, Sellers EM, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-245\r\n[10]\tDanan G, Benichou C. Causality assessment of adverse reactions to drugs—I. A novel method based on the conclusions of international consensus meetings: application to drug-induced liver injuries. J Clin Epidemiol 1993;46:1323-30. \r\n[11]\tAmerican Botanical Council. The complete German Commission E monographs therapeutic guide to herbal medicines 1999. Newton, MA: Integrative Medicine Communications, 1999:80-81.\r\n[12]\tEsteban A, Zapata JM, Casano L, Martin M, Sabater B. Peroxidase activity in Aloe barbadensis commercial gel: probable role in skin protection. Planta Med 2000;66:724-727. \r\n[13]\tSabeh F, Wright T, Norton SJ. Isozymes of superoxide dismutase from Aloe vera. Enzyme Protein 1996;49:212-221. \r\n[14]\tLangmead L, Feakins RM, Goldthorpe S. Randomized, double-blind, placebo-controlled trial of oral aloe vera gel for active ulcerative colitis. Aliment Pharmacol Ther. 2004;19:739-747. \r\n" relation_type: [] relation_uri: [] reportno: ~ rev_number: 18 series: ~ source: ~ status_changed: 2011-05-02 15:52:32 subjects: - JOURNALS succeeds: ~ suggestions: ~ sword_depositor: ~ sword_slug: ~ thesistype: ~ title: Viral Hepatitis And Enzyme Study type: journalp userid: 13352 volume: 1