?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Sphingosomes+a+novel+approach+to+vesicular+drug+delivery&rft.creator=Swarnlata+Saraf.%2C+Deepankar+Gupta%2C+Chanchal+Deep+Kaur%2C+Shailendra+Saraf%2C+Int+J+Cur+Sci+Res.+&rft.subject=JOURNALS&rft.description=Vesicular+systems+have+been+realized+as+extremely+useful+carrier+systems+in+various+scientific+domains.+Sphingosomes+is+bilayered+vesicles+in+which+an+aqueous+volume+is+entirely+enclosed+by+membrane+lipid+bilayer+mainly+composed+of+natural+or+synthetic+sphingolipid.+Sphingosomes+solve+the+major+drawback+of+vesicle+system+(liposomes%2C+niosomes)+like+less+stability%2C+less+in+vivo+circulation+time%2C+low+tumor+loading+efficacy+in+case+of+cancer+therapy.+Sphingosomes+are+clinically+used+delivery+system+for+chemotherapeutic+agent%2C+biological+macromolecule+and+diagnostics.+Due+to+flexibility+in+size+and+composition%2C+different+types+of+sphingosomes+have+been+developed.+The+out+come+of+this+review+is+that+sphingosomes+represents+a+promising+vesicular+drug+delivery+system+to+delivers+therapeutic+compounds+for+a+range+of+possible+applications.&rft.publisher=CurrentSciDirect+Publications&rft.date=2011-04-30&rft.type=Journal+(Paginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F7311%2F1%2FSphingosomes_a_novel_approach_to_vesicular_drug_delivery.pdf&rft.identifier=++Swarnlata+Saraf.%2C+Deepankar+Gupta%2C+Chanchal+Deep+Kaur%2C+Shailendra+Saraf%2C+Int+J+Cur+Sci+Res.+++(2011)+Sphingosomes+a+novel+approach+to+vesicular+drug+delivery.++%5BJournal+(Paginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F7311%2F