--- abstract: 'Introduction: Neonatal septicaemia is one among the leading causes of neonatal mortality in India. For the last 20 years CoNS has been identified as a major cause of neonatal septicaemia in NICU. Different studies show 70-75% of CoNS as resistant to methicillin. Material and methods: Blood samples from neonatal septicaemia cases during Dec 2007 to Dec 2010 were processed & isolates were identified. CoNS were biotyped & methicillin resistance was detected using cefoxitin 30 µg disk. Results: Of 2256 blood samples from neonatal septicaemia cases, 587(36.98%) were CoNS. Staphylococcus epidermidis 234(39.86%) was the commonest isolate. Methicillin resistance was noted in 286 (48.72%). MRCoNS prevalence during 2008, 2009 & 2010 were 41.57%, 47% and 57.36% respectively. Conclusion: Our study showed increased trends of MR-CoNS in neonatal septicaemia leading to increased usage of vancomycin & other glycopeptides, resulting in emergence of multidrug resistant strains, thus narrowing the treatment options in neonates.' altloc: - http://www.ojhas.org/issue36/2010-4-11.htm chapter: ~ commentary: ~ commref: ~ confdates: ~ conference: ~ confloc: ~ contact_email: ~ creators_id: - drdeepa_intel@yahoo.co.in - ~ - ~ creators_name: - family: S given: Deepa honourific: '' lineage: '' - family: B given: Amruta Kumari honourific: '' lineage: '' - family: D given: Venkatesha honourific: '' lineage: '' date: 2011-01-20 date_type: published datestamp: 2011-05-02 17:17:12 department: ~ dir: disk0/00/00/72/54 edit_lock_since: ~ edit_lock_until: 0 edit_lock_user: ~ editors_id: - BS Kakkilaya editors_name: - family: Kakkilaya given: Srinivas honourific: Dr lineage: '' eprint_status: archive eprintid: 7254 fileinfo: /style/images/fileicons/application_pdf.png;/7254/1/2010%2D4%2D11.pdf full_text_status: public importid: ~ institution: ~ isbn: ~ ispublished: pub issn: ~ item_issues_comment: [] item_issues_count: 0 item_issues_description: [] item_issues_id: [] item_issues_reported_by: [] item_issues_resolved_by: [] item_issues_status: [] item_issues_timestamp: [] item_issues_type: [] keywords: Neonatal septicaemia; Coagulase Negative Staphylococcus; Methicillin resistance lastmod: 2011-05-02 17:17:12 latitude: ~ longitude: ~ metadata_visibility: show note: ~ number: 4 pagerange: ~ pubdom: TRUE publication: Online Journal of Health and Allied Sciences publisher: BS Kakkilaya refereed: TRUE referencetext: "1.\tSundaram V, Kumar P, Dutta S etal . 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Prevalence of methicillin resistant, CoNS in neonatal intensive care units: findings from a tertiary care hospital in India. Med Microbiol 2004;53:941-944.\r\n12.\tStoll B, Gordon J. Late onset septicaemia in VLBW neonates A report from the National institute of child health & human development, neonatal research network. J Pediatr 1996;129:63-71.\r\n13.\tSohn A, Garrett D, Sinkowitz, Cochran R. Prevalence of nosocomial infections in NICU patients: results from the first national point prevalence survey. J Pediatr. 2001;136:821-827.\r\n14.\tKoksal F, Yasar H, Samarti M. Antibiotic resistant pattern of CoNS from blood cultures of septicaemia in Turkey. J Microbiol Res 2007;16:31-34." relation_type: [] relation_uri: [] reportno: ~ rev_number: 18 series: ~ source: ~ status_changed: 2011-05-02 17:17:12 subjects: - OJHAS succeeds: ~ suggestions: ~ sword_depositor: ~ sword_slug: ~ thesistype: ~ title: 'Increasing Trends of Methicillin Resistant Coagulase Negative Staphylococcus in Neonatal Septicaemia - A Study in a Tertiary Care Hospital, Mysore, South India' type: journale userid: 4338 volume: 9