---
abstract: 'Malignant melanoma is one of the rare and highly aggressive diseases of the sinonasal cavity. High index of suspicion is required for diagnosis as the patient usually presents with non specific signs and symptoms. In the natural course of the disease, higher rate of loco regional recurrences and distant metastasis are seen making the overall prognosis of disease very poor. In reviewing the various treatment modalities used in the past, surgical resection of the tumour with postoperative radiotherapy is preferred one. Advances in surgery, radiotherapy and chemotherapy don’t have any impact on improved survival, which remains poor in this disease. We report two cases of malignant melanoma, which were treated at our institute.'
altloc:
  - http://www.ojhas.org/issue32/2009-4-13.htm
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  - sbent224@gmail.com
  - ~
  - ~
  - ~
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creators_name:
  - family: Bhagat
    given: S
    honourific: ''
    lineage: ''
  - family: Varshney
    given: S
    honourific: ''
    lineage: ''
  - family: Singh
    given: R
    honourific: ''
    lineage: ''
  - family: Bist
    given: SS
    honourific: ''
    lineage: ''
  - family: Gupta
    given: N
    honourific: ''
    lineage: ''
date: 2010-04-30
date_type: published
datestamp: 2010-09-13 03:53:51
department: ~
dir: disk0/00/00/69/85
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editors_id:
  - Kakkilaya BS
editors_name:
  - family: Kakkilaya
    given: Srinivas
    honourific: Dr
    lineage: ''
eprint_status: archive
eprintid: 6985
fileinfo: /style/images/fileicons/application_pdf.png;/6985/1/2009%2D4%2D13.pdf
full_text_status: public
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keywords: 'Malignant Melanoma, Nose, Paranasal sinuses'
lastmod: 2011-03-11 08:57:42
latitude: ~
longitude: ~
metadata_visibility: show
note: ~
number: 4
pagerange: ~
pubdom: TRUE
publication: Online Journal of Health and Allied Sciences
publisher: Dr. BS Kakkilaya
refereed: TRUE
referencetext: "1.\tManolidis S, Donald PJ. Malignant mucosal melanoma of the head and neck: review of literature and report of 14 patients. Cancer 1997;80:1373-86.\r\n2.\tBridger AG, Smee D, Baldwin MAR et al. Experience with mucosal melanoma of the nose and paranasal sinuses. ANJ Surg. 2005;75:192-197.\r\n3.\tDwivedi R, Dwivedi R, Kazi R. Mucosal melanoma of nasal cavity and paranasal sinus: case report. J Cancer Res Ther. 2008;4:200-202.\r\n4.\tGoldsmith HS, Melanoma: An overview. CA Cancer J Clin 1979;29:194-215.\r\n5.\tMcKinnon JG, Kokal WA, Neifeld JP et al. Natural history and treatment of mucosal melanoma. J Surg Oncol.1989;41:222-5.\r\n6.\tStern SJ, Guillamondegui OM, Mucosal melanoma of the head and neck. Head Neck 1991;13:22-7.\r\n7.\tSanderson AR, Gaylis B. Malignant melanoma of the sinonasal mucosa: Two case reports and review. ENT-Ear, Nose & Throat Journal. 2007;86:287-290.\r\n8.\tDauer HE, Lewis JE, Rohlinger LA et al. Sinonasal melanoma: A clinicopathological review of 61 cases. Otolaryngology-Head and neck Surgery: 2008; 238:347-352.\r\n9.\tVolpe NJ, Albert DM. Metastatic and secondary orbital tumours. In Albert DM, Jackobeic FA, editors. Principles and practice of ophthalmology. 2nd ed. Phildelphia; W.B. Saunders. 2000. pp3218.\r\n10.\tChang AE, Karnell LH, Menck HR. The National Cancer Data Base report on cutaneous and noncutaneous melanoma: A summary of 84,836 cases from the past decade. The American college of Surgeons commission on Cancer and the American Cancer Society. Cancer. 1998;83(8):1664-78.\r\n11.\tTemam S, Mamelle G, Marandas P, et al. Postaperative radiotherapy for primary mucosal melanomas of the head and neck. Cancer 2005;103:313-9.\r\n12.\tKingdom TT, Kaplan MJ. Mucosal melanoma of nasal cavity and paranasal sinuses. Head Neck 1995;17:184-9."
relation_type: []
relation_uri: []
reportno: ~
rev_number: 20
series: ~
source: ~
status_changed: 2010-09-13 03:53:51
subjects:
  - OJHAS
succeeds: ~
suggestions: ~
sword_depositor: ~
sword_slug: ~
thesistype: ~
title: 'Malignant Melanoma of Nose and Paranasal Sinuses: 2 Case Reports'
type: journale
userid: 4338
volume: 8
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