?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Malignant+Melanoma+of+Nose+and+Paranasal+Sinuses%3A+2+Case+Reports&rft.creator=Bhagat%2C+S&rft.creator=Varshney%2C+S&rft.creator=Singh%2C+R&rft.creator=Bist%2C+SS&rft.creator=Gupta%2C+N&rft.subject=Online+Journal+of+Health+and+Allied+Sciences&rft.description=Malignant+melanoma+is+one+of+the+rare+and+highly+aggressive+diseases+of+the+sinonasal+cavity.+High+index+of+suspicion+is+required+for+diagnosis+as+the+patient+usually+presents+with+non+specific+signs+and+symptoms.+In+the+natural+course+of+the+disease%2C+higher+rate+of+loco+regional+recurrences+and+distant+metastasis+are+seen+making+the+overall+prognosis+of+disease+very+poor.+In+reviewing+the+various+treatment+modalities+used+in+the+past%2C+surgical+resection+of+the+tumour+with+postoperative+radiotherapy+is+preferred+one.+Advances+in+surgery%2C+radiotherapy+and+chemotherapy+don%E2%80%99t+have+any+impact+on+improved+survival%2C+which+remains+poor+in+this+disease.+We+report+two+cases+of+malignant+melanoma%2C+which+were+treated+at+our+institute.&rft.publisher=Dr.+BS+Kakkilaya&rft.contributor=Kakkilaya%2C+Dr+Srinivas&rft.date=2010-04-30&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F6985%2F1%2F2009-4-13.pdf&rft.identifier=++Bhagat%2C+S+and+Varshney%2C+S+and+Singh%2C+R+and+Bist%2C+SS+and+Gupta%2C+N++(2010)+Malignant+Melanoma+of+Nose+and+Paranasal+Sinuses%3A+2+Case+Reports.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F6985%2F