creators_name: Adiga, MNS creators_name: Alwar, MC creators_name: Pai, MRSM creators_name: Adiga, US creators_id: ushachidu@yahoo.com editors_name: Kakkilaya, Srinivas editors_id: Kakkilaya BS type: journale datestamp: 2010-09-13 03:54:02 lastmod: 2011-03-11 08:57:42 metadata_visibility: show title: Pattern of antimicrobial agents use in hospital deliveries: A prospective comparative study ispublished: pub subjects: OJHAS full_text_status: public keywords: Antimicrobial agents, Infection, Prophylaxis, Hospital deliveries abstract: Objective: Drug utilization pattern identifies the problems that arise from the drug usage in health care delivery system and highlights the current approaches to the rational use of drugs. The present study evaluates the utilization pattern of antimicrobial agents in hospital deliveries of different setups. Methodology: Two hundred hospital deliveries from a government hospital GroupI (G-I) and 100 cases each from two private hospitals Group II & Group III (G II & G III) were studied. Groups, drugs, numbers of antimicrobials used, duration with indication for their use were the criteria taken into consideration for comparison. Results: Beta-lactams, nitroimidazoles and fluoroquinolones were commonly prescribed groups of antimicrobials. The duration of prophylaxis was 6.73±1.79, 5.77±1.10 &5.14±1.53 days in three groups respectively which was significantly different (p<0.01). Caesarian section, episiotomy were the commonest prophylactic indications. Conclusion: The present study calls for an urgent review on rational use of antimicrobial for prophylaxis. date: 2010-04-30 date_type: published publication: Online Journal of Health and Allied Sciences volume: 8 number: 4 publisher: Dr. BS Kakkilaya refereed: TRUE referencetext: 1. The selection of essential drugs. WHO technical report 1977; 615: 36. 2. Einarson TR, Bergman U, Wiholm BE. Principles and practice of pharmacoepidemiology. In: Speight TM, Holford NMG. Avery’s drug treatment. 4th ed. Auckland: Adis international Ltd. 1996: 371-92. 3. Buxton IOL. Principles of prescription order writing and patient compliance. In Brunton LL, Lazo JS, and Parker KL. Goodman & Gillman’s The pharmacological basis of therapeutics. 11th ed. Mc Graw-Hill Press, New York, 2006. pp.1777-86. 4. Kulshrestha S, Aggrawal KK. Survey of pattern of antimicrobial use in teaching hospital. Ind J Pharmacol 1984;16(1): 395. 5. Avron J, Chen M, Hartley R. Scientific versus commercial sources of influence on the prescribing behaviour of physician. The Am J Med 1982;73:4-8. 6. Kunin CM. Rational use of antibiotics. WHO drug information. 1990;4(1):4-7. 7. Col NF, O’Connor RW. Estimating world wide current antibiotic usage. Report of task force. Rev Infect Dis 1987;9(3):232-43. 8. Laporte JR. Towards a healthy use of pharmaceuticals. Development dialogue 1995;2:48-55. 9. Haddad NG, Calder AA. Infection following Caesarean section. In MacLean AB. Clinical Infections in Obstetrics and Gynaecology 1st ed. Blackwell. Oxford. 1990. pp. 160-71. 10. Rehan HS, Nagarani MA, Rehan Moushumi. A study on drug prescribing pattern and use of antimicrobial agent at a tertiary care teaching hospital in Eastern Nepal. Ind J Pharmacol 1988;30:175-80. 11. Srishyla MV, Nagarani MA, Damodar S, Venkataraman BV, Nandakumar MJ. A preliminary audit of practice: antibacterial prophylaxis in general surgery in an Indian hospital setting. Ind J Physiol Pharmacol 1994;38:207-10. 12. Wilkowske CJ. General principles of antimicrobial therapy. Mayo Clin Proc 1991;66:931-41. 13. Srishyla MV, Nagarani MA, Venkataraman BV. Drug utilization of antimicrobials in the patient setting of a tertiary hospital. Ind J Pharmacol 1994;26(4):282-87 14. Chambers HF. General Principles of antimicrobial therapy. In Brunton LL, Lazo JS, Parker KL. Goodman and Gillman’s The pharmacological basis of therapeutics 11thed. Mc Graw Hill Press, New York, 2006. pp. 1095-1110. citation: Adiga, MNS and Alwar, MC and Pai, MRSM and Adiga, US (2010) Pattern of antimicrobial agents use in hospital deliveries: A prospective comparative study. [Journal (On-line/Unpaginated)] document_url: http://cogprints.org/6981/1/2009-4-10.pdf