?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Intervention+and+Prevention+of+Hereditary+Hemolytic+Disorders+in+Two+Ethnic+Communities+of+Sundargarh+District+of+Orissa%2C+India%3A+An+Experience+from+KAP+Studies&rft.creator=Balgir%2C+RS&rft.subject=Online+Journal+of+Health+and+Allied+Sciences&rft.description=Hereditary+hemolytic+disorders+are+important+public+health+challenges+in+India.+They+cause+a+high+degree+of+morbidity%2C+mortality+and+fetal+wastage+in+vulnerable+communities.+Tradition-bound-psychosocial+influences+are+detrimental+to+the+process+of+prevention.+This+study+was+designed+to+create+awareness%2C+motivate%2C+and+sensitize+two+major+vulnerable+tribal+communities%3A+Bhuyan+and+Kharia+for+hemoglobin+and+allied+hemolytic+disorders+in+addition+to+imparting+prospective+and+retrospective+genetic%2Fmarriage+counseling.+Bhuyan+and+Kharia+tribal+people+in+Orissa+live+in+clusters+practicing+inter-village+tribal+endogamy+and+clan+exogamy.+For+the+present+study%2C+random+sampling+procedure+for+the+selection+of+whole+village+was+followed.+Imparting+of+education%2C+motivation+and+sensitization+for+carrier+detection+were+carried+out+through+IEC+materials%2C+holding+interactive+meetings+and+discussions+at+district%2C+block+and+village+levels.+Both+prospective+and+retrospective+intervention+and+genetic%2Fmarriage+counseling+was+done+through+the+local+PHC+doctor.+The+pre-+and+post-intervention+knowledge%2C+attitude+and+practice+(KAP)+studies+were+conducted.+Tribal+people+were+not+knowing+the+signs+and+symptoms+of+sickle+cell+disease+(2.1%25)+and+beta-thalassemia+(1.0%25)%2C+but+after+IEC%2C+their+knowledge+was+considerably+improved+(67.8%25%2C+56.4%25%2C+respectively).+Sickle+cell+patient+needs+treatment+(37.6%25)+like+folic+acid%2C+blood+transfusion%2C+etc.+Beta-thalassemia+is+disease+causes+bloodlessness+and+is+a+transfusion+dependent+(73.2%25).+All+patients+of+thalassemia+major+or+sickle+cell+disease+have+carrier+parents+and+carriers+do+not+suffer+from+any+clinical+ailments.+After+intervention%2C+it+was+known+that+G-6-PD+is+an+enzyme%2C+which+helps+in+glucose+metabolism+of+red+cells+(76.4%25)+and+its+hereditary+deficiency+causes+hemolytic+anemia%2C+jaundice+and+black+urination+(73.8%25)+in+malaria+cases+when+anti-malarials+are+administered.+Methodical+and+prudent+intervention+and+preventive+strategies+found+positive+and+encouraging+impact+on+the+affected+people.+Success+of+strategy+showed+apparent+overwhelming+response+of+the+tribal+people+towards+changing+the+traditional+mindset+and+improving+their+health+and+quality+of+life.&rft.publisher=Dr.+B.S.+Kakkilaya&rft.contributor=Kakkilaya%2C+Dr+Srinivas&rft.date=2010-10-15&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F6980%2F1%2F2010-3-4.pdf&rft.identifier=++Balgir%2C+RS++(2010)+Intervention+and+Prevention+of+Hereditary+Hemolytic+Disorders+in+Two+Ethnic+Communities+of+Sundargarh+District+of+Orissa%2C+India%3A+An+Experience+from+KAP+Studies.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F6980%2F