creators_name: Meshram, II creators_name: Hiwarkar, PA creators_name: Kulkarni, PN creators_id: indrapal.m@rediffmail.com editors_name: Kakkilaya, Srinivas editors_id: Kakkilaya BS type: journale datestamp: 2010-09-13 03:56:22 lastmod: 2011-03-11 08:57:40 metadata_visibility: show title: Reproductive Risk Factors for Breast Cancer: A Case Control Study ispublished: pub subjects: OJHAS full_text_status: public abstract: Background: Breast cancer is second most important cancer among Indian women. Although risk factors are not much prevalent as in western countries, incidence rate is increasing in India. The study was undertaken to study various risk factors associated with breast cancer. Methods: A hospital based group matched case control study was undertaken to identify risk factors. The study consisted of 105 hospitalized cases confirmed on histopathology and 210 group matched controls selected from urban field practice area, Sadar, without any malignancy. Bivariate analyses included odds ratio (OR), 95% confidence interval (CI) for odds ratio. Results: Earlier age at menarche ≤ 12 years of age, late age at first full term delivery, nulliparity, Lack of breast-feeding were found to be significantly associated with the risk of breast cancer in both pre menopausal & post menopausal women while age at menopause at or after 50 years was significantly associated with the risk in post menopausal women. Conclusions: Study suggests that the changes in menstrual and reproductive patterns among women i.e. early age at menarche and late age at first childbirth and some environmental factors in Central India may have contributed to the increase in breast cancer risk, particularly among younger women. date: 2009-11-15 date_type: published publication: Online Journal of Health and Allied Sciences volume: 8 number: 3 publisher: Dr. B.S. Kakkilaya refereed: TRUE referencetext: 1. World Health Organization. Facts sheet No. 297: Cancer 2006. 2. Cancer. 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