creators_name: Kalra, Sanjay creators_id: brideknl@gmail.com editors_name: Jalalian, Mehrdad type: journalp datestamp: 2009-11-14 11:39:39 lastmod: 2011-03-11 08:57:30 metadata_visibility: show title: The role of Coenzyme Q10 in statin-associated myopathy ispublished: pub subjects: JOURNALS full_text_status: public keywords: statin, myalgia, myopathy, Coenzyme Q abstract: Statins, or 3-hydroxyl-3-methylglutaryl coenzyme HMG-CoA reductase inhibitors, are cholesterol-lowering drugs which are frequently used in the primary and secondary prevention of coronary artery disease. Current research and recommendations support and encourage more extensive use of these drugs. However, statin usage is limited by many factors, including a high incidence of statin-associated myalgia and myopathy. 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Coenzyme Q10 does not improve simvastatin tolerability in dyslipidemic patients with prior statin-induced myalgia AHA 2006. Circulation 2007; 114: II41. 38. Levy HB, Kohlhaas HK. Considerations for supplementing with Coenzyme Q10 during statin therapy. The Annals of Pharmacotherapy 2006; 40(2):290-294. citation: Kalra, Dr Sanjay (2009) The role of Coenzyme Q10 in statin-associated myopathy. [Journal (Paginated)] document_url: http://cogprints.org/6668/1/2-8.pdf