title: Placenta Ingestion Enhances Analgesia Produced by Vaginal/Cervical Stimulation in Rats creator: Kristal, Dr. Mark B. creator: Thompson, Alexis C. creator: Heller, Steve B. creator: Komisaruk, Dr. Barry R. subject: Behavioral Biology subject: Psychobiology subject: Physiological Psychology subject: Behavioral Neuroscience description: Ingestion of placenta has previously been shown to enhance opiate-mediated analgesia (measured as tail-flick latency) induced either by morphine injection or by footshock. The present study was designed to test whether placenta ingestion would enhance the partly opiate-mediated analgesia produced by vaginal/cervical stimulation. Nulliparous Sprague-Dawley rats were tested for analgesia, using tail-flick latency, during and after vaginal/cervical stimulation; the tests for vaginal/cervical stimulation-induced analgesia were administered both before and after the rats ate placenta or ground beef. Placenta ingestion, but not beef ingestion. significantly heightened vaginal/cervical stimulation-induced analgesia. A subsequent morphine injection provided evidence that, as in a previous report, placenta ingestion, but not beef ingestion, enhanced morphine-induced analgesia. publisher: Pergamon Press date: 1986 type: Journal (Paginated) type: PeerReviewed format: application/pdf identifier: http://cogprints.org/6254/1/VSIA.pdf identifier: Kristal, Dr. Mark B. and Thompson, Alexis C. and Heller, Steve B. and Komisaruk, Dr. Barry R. (1986) Placenta Ingestion Enhances Analgesia Produced by Vaginal/Cervical Stimulation in Rats. [Journal (Paginated)] relation: http://cogprints.org/6254/