?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=SIMULATION+IN+NEUROBIOLOGY+--+THEORY+OR+EXPERIMENT%3F&rft.creator=Amit%2C+Daniel+J.&rft.subject=Computational+Neuroscience&rft.subject=Computational+Neuroscience&rft.subject=Neural+Modelling&rft.subject=Neurophysiology&rft.description=Investigation+in+neurophysiology+usually+involves+measurements+of+large+population+average+signals+or+small+sample+recordings.+There+is+an+underlying+assumption+that+the+observations+express+activity+of+large+groups+of+similarly+acting+neurons+that+is+the+result+of+a+bottom-up+scenario+in+which+individual+cells%2C+via+their+synaptic+interactions%2C+lead+to+the+large+scale+phenomena.+The+connection+between+the+levels+must+be+provided+by+theory%2C+which+must+also+provide+the+relevant+variables+to+observe.+It+is+suggested+that+between+the+experiment+and+the+full+theory+there+is+a+creative%2C+mixed+role+for+simulation%3A+both+experimental+and+theoretical.+A+simulation+presents+complex+dynamics+and+hence+is+an+empirical+board+for+testing+theoretical+tools%2C+yet+its+controlled+behavior+can+make+predictions+about+the+biological+system.&rft.date=1998&rft.type=Journal+(Paginated)&rft.type=PeerReviewed&rft.format=application%2Fpostscript&rft.identifier=http%3A%2F%2Fcogprints.org%2F61%2F2%2Fsimu3.ps&rft.identifier=++Amit%2C+Daniel+J.++(1998)+SIMULATION+IN+NEUROBIOLOGY+--+THEORY+OR+EXPERIMENT%3F++%5BJournal+(Paginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F61%2F