<> "The repository administrator has not yet configured an RDF license."^^ . <> . . "Analgesic Efficacy of Orally Administered\r\nBuprenorphine in Rats"^^ . "The analgesic effect of orally administered buprenorphine was compared with that induced by a standard\r\ntherapeutic injected dose (0.05 mg/kg of body weight, s.c.) in male Long-Evans rats. Analgesia was assessed by\r\nmeasuring pain threshold, using the hot-water tail-flick assay before and after administration of buprenorphine.\r\nThe results suggest that a commonly used formula for oral buprenorphine in flavored gelatin, at a dose of 0.5\r\nmg/kg, does not increase pain threshold in rats. Instead, oral buprenorphine doses of 5 and 10 mg/kg were\r\nnecessary to induce significant increases in pain threshold. However, these doses had to be administered by\r\norogastric infusion because the rats would not voluntarily eat flavored gelatin containing this much buprenorphine.\r\nThe depth of analgesia induced by these infused doses was comparable to that induced by the clinically effective\r\ns.c. treatment (0.05 mg/kg)."^^ . "2001-02" . . "51" . "1" . . "American Association for Laboratory Animal Science"^^ . . . "Comparative Medicine"^^ . . . . . . . . . . . . . . . . . "Mark B."^^ . "Kristal"^^ . "Mark B. Kristal"^^ . . "Thomas"^^ . "Martin"^^ . "Thomas Martin"^^ . . "Lisa B.E."^^ . "Martin"^^ . "Lisa B.E. Martin"^^ . . "Alexis C."^^ . "Thompson"^^ . "Alexis C. Thompson"^^ . . . . . . "Analgesic Efficacy of Orally Administered\r\nBuprenorphine in Rats (PDF)"^^ . . . . . . . . . "buprenorphine.pdf"^^ . . . "Analgesic Efficacy of Orally Administered\r\nBuprenorphine in Rats (Image (PNG))"^^ . . . . . . "preview.png"^^ . . . "Analgesic Efficacy of Orally Administered\r\nBuprenorphine in Rats (Indexer Terms)"^^ . . . . . . "indexcodes.txt"^^ . . "HTML Summary of #5722 \n\nAnalgesic Efficacy of Orally Administered \nBuprenorphine in Rats\n\n" . "text/html" . . . "Behavioral Neuroscience" . .