creators_name: Segev, Ronen
creators_name: Ben-Jacob, Eshel
type: journalp
datestamp: 1998-08-06
lastmod: 2011-03-11 08:53:38
metadata_visibility: show
title: From Neurons to Brain: Adaptive Self-Wiring of Neurons
ispublished: pub
subjects: bio-phys
subjects: bio-theory
subjects: comp-neuro-sci
subjects: comp-sci-mach-dynam-sys
subjects: neuro-anat
subjects: neuro-mod
subjects: neuro-physio
full_text_status: public
keywords: excitable wave, self-wiring, neural networks, growth cone, chemotaxis
abstract: During embryonic morpho-genesis, a collection of individual neurons turns into a functioning network with unique capabilities. Only recently has this most staggering example of emergent process in the natural world, began to be studied. Here we propose a navigational strategy for neurites growth cones, based on sophisticated chemical signaling. We further propose that the embryonic environment (the neurons and the glia cells) acts as an excitable media in which concentric and spiral chemical waves are formed. Together with the navigation strategy, the chemical waves provide a mechanism for communication, regulation, and control required for the adaptive self-wiring of neurons.
date: 1998-04
date_type: published
publication: Journal of Complex Systems
volume: 1
number: 1
pagerange: 00
refereed: TRUE
citation:   Segev, Ronen and Ben-Jacob, Eshel  (1998) From Neurons to Brain: Adaptive Self-Wiring of Neurons.  [Journal (Paginated)]     
document_url: http://cogprints.org/57/2/from_neurons.ps