--- abstract: | After discovering two families with handicapped children exhibiting the “Uner Tan syndrome,” the author discovered a man exhibiting only wrist-walking with no primitive mental abilities including language. According to his mother, he had an infectious disease with high fever as a three months old baby; as a result, the left leg had been paralyzed after a penicilline injection. This paralysis most probably resulted from a viral disease, possibly poliomyelitis. He is now (2006) 36 years old; the left leg is flaccid and atrophic, with no tendon reflexes; however, sensation is normal. The boy never stood up on his feet while maturing. The father forced him to walk upright using physical devices and making due exercises, but the child always rejected standing upright and walking in erect posture; he always preferred wrist-walking; he expresses that wrist-walking is much more comfortable for him than upright-walking. He is very strong now, making daily body building exercises, and walking quite fast using a “three legs,” although he cannot stand upright. Mental status, including the language and conscious experience, is quite normal. There was no intra-familiar marriage as in the two families mentioned earlier, and there is no wrist-walking in his family and relatives. There were no cerebellar signs and symptoms upon neurological examination. The brain-MRI was normal; there was no atrophy in cerebellum and vermis. It was concluded that there may be sporadic wrist-walkers exhibiting no “Uner Tan Syndrome.” The results suggest that the cerebellum has nothing to do with human wrist-walking, which may rather be an atavistic trait appearing from time to time in normal individuals, altloc: - http://www.taylorandfrancis.com chapter: ~ commentary: ~ commref: ~ confdates: ~ conference: ~ confloc: ~ contact_email: ~ creators_id: [] creators_name: - family: TAN given: Üner honourific: Prof. Dr. lineage: '' date: 2007-01 date_type: published datestamp: 2007-02-19 department: ~ dir: disk0/00/00/53/83 edit_lock_since: ~ edit_lock_until: ~ edit_lock_user: ~ editors_id: [] editors_name: - family: Hyden given: Holger V. honourific: Prof. lineage: '' - family: Renji given: Ennio de honourific: Prof. lineage: '' - family: Tan given: Uner honourific: Prof. lineage: '' eprint_status: archive eprintid: 5383 fileinfo: /style/images/fileicons/application_pdf.png;/5383/1/WRIST_WALKER_NO_UT_SYND.pdf full_text_status: public importid: ~ institution: ~ isbn: ~ ispublished: pub issn: ~ item_issues_comment: [] item_issues_count: 0 item_issues_description: [] item_issues_id: [] item_issues_reported_by: [] item_issues_resolved_by: [] item_issues_status: [] item_issues_timestamp: [] item_issues_type: [] keywords: 'brain, cerebellum, vermis, Uner Tan Syndrome, gait, wrist-walking, evolution, poliomyelitis' lastmod: 2011-03-11 08:56:46 latitude: ~ longitude: ~ metadata_visibility: show note: ~ number: 1 pagerange: 147-156 pubdom: TRUE publication: International Journal of Neuroscience publisher: Taylor and Francis refereed: TRUE referencetext: | 156 ¨U. TAN Teotonio, H., & Rose, M. R. (2000). Variation in the reversibility of evolution. Nature, 408, 463–466. Teotonio, H., & Rose, M. R. (2001). Perspective: Reverse evolution. Evolution, 55, 653–660. Teotonio, H., & Rose, M. R. (2002). Reverse evolution of fitness in Drosophila melanogaster. Journal of Evolutionary Biology, 15, 608–617. Turkmen, S., Demirhan, O., Hoffmann, K., Diers, A., Zimmer, C., Sperling, K., & Mundlos, S. (2006). Journal of Medical Genetics, 43, 461–464. relation_type: [] relation_uri: [] reportno: ~ rev_number: 12 series: ~ source: ~ status_changed: 2007-09-12 17:09:28 subjects: - neuro-physio - evol-psy succeeds: ~ suggestions: ~ sword_depositor: ~ sword_slug: ~ thesistype: ~ title: | A WRIST-WALKER EXHIBITING NO "UNER TAN SYDNROME": A THEORY FOR POSSIBLE MECHANISMS OF HUMAN DEVOLUTION TOWARD THE ATAVISTIC WALKING PATTERNS type: journalp userid: 4979 volume: 117