?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Prenatal+growth+markers+in+schizophrenia%3A+a+monozygotic+co-twin+control+study.%0A&rft.creator=Davis%2C+JO&rft.creator=Bracha%2C+HS&rft.subject=Neuropsychiatry&rft.subject=Neurology&rft.description=OBJECTIVE%3A+This+co-twin+study+investigated+monozygotic+twins+who+were+discordant+for+schizophrenia+for+evidence+of+prenatal+growth+differences+between+the+affected+and+well+co-twins.+METHOD%3A+Four+dermatoglyphic+markers+of+prenatal+growth+were+obtained+by+established+procedures+from+26+monozygotic+twin+pairs+discordant+for+schizophrenia%2C+13+monozygotic+twin+pairs+concordant+for+schizophrenia%2C+and+several+normal+monozygotic+twin+samples.+RESULTS%3A+The+a-b+ridge+count+differences+between+the+affected+and+well+co-twins+were+greater+than+those+found+for+concordant+and+normal+monozygotic+pairs.+In+comparison+with+their+well+co-twins%2C+the+affected+twins%2C+in+discordant+pairs%2C+had+developed+fewer+epidermal+ridges+in+the+a-b+interdigital+area+of+their+right+palms.+In+contrast%2C+no+significant+differences+were+found+between+the+affected+twins+and+their+well+co-twins+on+markers+associated+with+fetal+development+before+13+or+after+15+weeks+estimated+gestational+age.+CONCLUSIONS%3A+Because+the+a-b+ridges+are+known+to+complete+development+between+13+and+15+weeks+estimated+gestational+age%2C+the+results+provide+physical+evidence+suggesting+that+the+schizophrenia-affected+monozygotic+twins+alone+experienced+a+time-specific+and+time-limited+dysgenesis+during+this+time.+Commonalities+in+the+ontogeny+of+epidermal+and+neurological+structures+are+discussed.&rft.date=1996-09&rft.type=Journal+(Paginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F5312%2F1%2FBracha_et_al.%252C_Prenatal_Growth_Markers_-_Am_J_Psych_1996.PDF&rft.identifier=++Davis%2C+JO+and+Bracha%2C+HS++(1996)+Prenatal+growth+markers+in+schizophrenia%3A+a+monozygotic+co-twin+control+study.++%5BJournal+(Paginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F5312%2F