title: Subclinical microcrania, subclinical macrocrarnia, and fifth-month fetal markers (of growth retardation or edema) in schizophrenia: a co-twin control study of discordant monozygotic twins.
creator: Bracha, HS
creator: Gil, P
creator: Lange, B
creator: Gilder, J
creator: Torrey, EF
creator: Gottesman, II
creator: McCray, DS
subject: Neuropsychiatry
subject: Neurology
description: Summary: We tested the hypothesis that gestational injuries in some patients with schozophrenia would leave their mark as a subtle reduction in head circumference (subclinical microcrania).    Conclusions: The head circumferences of all subjects were in the normal range.  Decreased head circumference in affected MZ co-twins (relative to unaffected MZ co-twin) characteriazes discordant MZ pairs with larger finger-ridge-count differences (i.e., second-trimester fetal-size differences).  This study using ideal genetic controls suggests that, while present only in some patients with schizophrenia, the decrease in head circumference is most likely a consequence of in-utero nonshared environmental deleterious events manifesting as groth retardation or as fetal edema and occurring around the fifth prenatal month.  
date: 1995
type: Journal (Paginated)
type: NonPeerReviewed
format: application/pdf
identifier: http://cogprints.org/5300/1/Bracha_et_al.%2C_Subclinical_microcrania%2C_subclinical_macrocrarnia%2C_and_fifth-month_fetal_markers_%28of_growth_retardation_or_edema%29_in_schizophrenia_a_co-twin_control_study_of_discordant_monozygotic_twins..PDF
identifier:   Bracha, HS and Gil, P and Lange, B and Gilder, J and Torrey, EF and Gottesman, II and McCray, DS  (1995) Subclinical microcrania, subclinical macrocrarnia, and fifth-month fetal markers (of growth retardation or edema) in schizophrenia: a co-twin control study of discordant monozygotic twins.  [Journal (Paginated)]     
relation: http://cogprints.org/5300/