?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Comparison+of+insulin+resistance+by+indirect+methods+-+HOMA%2C+QUICKI+and+McAuley+-+with+fasting+insulin+in+patients+with+type+2+diabetes+in+Galle%2CSri+Lanka%3A+A+pilot+study&rft.creator=Menik+Hettihewa%2C+Dr.+Lukshmy&rft.creator=Palangasinghe%2C+Dr.+Shalika&rft.creator=S+Jayasinghe%2C+Dr.+Sudheera&rft.creator=W+Gunasekara%2C+Dr.+Sudari&rft.creator=P+Weerarathna%2C+Dr.+Thilak&rft.subject=Online+Journal+of+Health+and+Allied+Sciences&rft.description=Background%3A+To+investigate+importance+of+fasting+insulin+(FI)+as+a+diagnostic+test+for+insulin+resistance+(IR)+and+to+compare+with+other+standard+methods+McAuley+(McA)%2C+HOMA+and+QUICKI+indices+in+Diabetes+Mellitus+(DM).%0AMethod%3A+42+diabetic+patients+who+have+been+already+diagnosed+were+used+in+our+study.+They+were+investigated+for+fasting+blood+glucose+(FBS)%2C+FI%2C+LDL%2C+Triglycerides+(TG)%2C+total+cholesterol+(TC)+and+HDL+levels.+IR+was+calculated+by+McA%2C+HOMA%2C+QUICKI+indices+and+by+FI.%0AResults%3A+81%25+of+patients+were+insulin+resistant+by+McA+and+FI+in+our+study+group.+93%25+were+detected+as+insulin+resistant+by+HOMA+and+QUICKI.+IR+by+FI+was+further+compared+with+HOMA+and+QUICKI+and+81%25+of+patients+were+found+to+be+insulin+resistant+by+FI%2C+HOMA+and+QUICKI.+Results+showed+that+there+was+a+significant+correlation+between+FI+and+McA+in+expressing+IR+in+our+study+group+(p+%3C0.01%2C+r+%3D+-0.849).+Further%2C+FI+had+a+statistically+significant+correlation+with+HOMA+and+QUICKI+indices+(p+%3C0.01%2C+r+%3D+0.906+and+p+%3C0.01+r+%3D+-0.822+respectively).%0AConclusion%3A+FI+measurement+alone+in+diabetic+patients+has+detected+IR+in+81%25+of+patients%2C+similar+to+the+other+standard+methods+(McA%3B+81%25%2C+HOMA+and+QUICKI%3B+93%25).+We+further+identified+that+FI+as+a+diagnostic+test+of+IR+had+substantial+correlation+with+McA.+Our+results+recommend+further+studies+to+see+the+possibility+of+taking+fasting+insulin+to+determine+IR+in+type+2+diabetic+population&rft.publisher=Dr.+B.S.+Kakkilaya&rft.contributor=Kakkilaya+Bevinje%2C+Dr.+Srinivas&rft.contributor=Baliga+B%2C+Dr.+Shatharam&rft.date=2006-07&rft.type=Journal+(On-line%2FUnpaginated)&rft.type=PeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F5000%2F1%2F2006-1-2.pdf&rft.identifier=++Menik+Hettihewa%2C+Dr.+Lukshmy+and+Palangasinghe%2C+Dr.+Shalika+and+S+Jayasinghe%2C+Dr.+Sudheera+and+W+Gunasekara%2C+Dr.+Sudari+and+P+Weerarathna%2C+Dr.+Thilak++(2006)+Comparison+of+insulin+resistance+by+indirect+methods+-+HOMA%2C+QUICKI+and+McAuley+-+with+fasting+insulin+in+patients+with+type+2+diabetes+in+Galle%2CSri+Lanka%3A+A+pilot+study.++%5BJournal+(On-line%2FUnpaginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F5000%2F