--- abstract: | Background: The implantable cardioverter defibrillators (ICDs) are increasingly being used as a treatment modality for life threatening tachyarrhythmia. The purpose of this study was to compare the frequency of complications and mortality between single-chamber and dual-chamber ICD implantation in Shahid Rajaie cardiovascular center. Methods and results: Between January 2000 and December 2004, 234 patients received ICD by a percutaneous transvenous approach and were followed for 33 ± 23 months. The cumulative incidence of complications was 9.4% over the follow-up period. There was no significant difference in overall complication rate between single chamber (VR) and dual chamber (DR) ICD groups in the follow-up period (P= 0.11). The risk of complications did not have any statistically significant difference in secondary versus primary prevention groups (P=0.06). The complications were not associated with the severity of left ventricular systolic dysfunction (P=0.16).The frequency of lead-related complications was higher in dual chamber ICDs in comparison with single chamber ICDs (P=0.02). There was no significant difference in mortality between different sex groups (P=0.37), different indications for ICD implantation (P=0.43) or between VR and DR ICD groups (P= 0.55). Predictors of mortality were NYHA class III or more (P<0.001), age >65 years (P=0.011) and LVEF<30% (P<0.001). The mortality in patients with CAD and DCM were significantly higher than those with other structural heart diseases (P=0.001). Conclusions: Close monitoring of patients during the first 2 month after ICD implantation is recommended because the majority of complications occur early after the procedure. altloc: - http://www.ipej.org/0602/bagherzadeh.htm chapter: ~ commentary: ~ commref: ~ confdates: ~ conference: ~ confloc: ~ contact_email: ~ creators_id: [] creators_name: - family: Bagherzadeh given: Ataallah honourific: '' lineage: '' - family: Emkanjoo given: Zahra honourific: '' lineage: '' - family: Haghjoo given: Majid honourific: '' lineage: '' - family: Farahani given: Maryam Moshkani honourific: '' lineage: '' - family: Alizadeh given: Abolfath honourific: '' lineage: '' - family: Sadr-Ameli given: Mohammad Ali honourific: '' lineage: '' date: 2006-04 date_type: published datestamp: 2006-04-01 department: ~ dir: disk0/00/00/48/00 edit_lock_since: ~ edit_lock_until: ~ edit_lock_user: ~ editors_id: [] editors_name: - family: Singh given: Balbir honourific: '' lineage: '' - family: Lokhandwala given: Yash honourific: '' lineage: '' - family: Francis given: Johnson honourific: '' lineage: '' - family: Gupta given: Anup honourific: '' lineage: '' - family: Ghosh given: Joydeep honourific: '' lineage: '' eprint_status: archive eprintid: 4800 fileinfo: /style/images/fileicons/text_html.png;/4800/1/bagherzadeh.htm|/style/images/fileicons/application_pdf.png;/4800/2/bagherzadeh.pdf full_text_status: public importid: ~ institution: ~ isbn: ~ ispublished: pub issn: ~ item_issues_comment: [] item_issues_count: 0 item_issues_description: [] item_issues_id: [] item_issues_reported_by: [] item_issues_resolved_by: [] item_issues_status: [] item_issues_timestamp: [] item_issues_type: [] keywords: 'implantable cardioverter-defibrillator; complication; mortality ' lastmod: 2011-03-11 08:56:22 latitude: ~ longitude: ~ metadata_visibility: show note: ~ number: 2 pagerange: 75-83 pubdom: TRUE publication: Indian Pacing and Electrophysiology Journal publisher: Indian Pacing and Electrophysiology Group refereed: TRUE referencetext: |- 1. Zipes DP, Roberts D. The Pacemaker Cardioverter Defibrillator Investigators. Results of the international study of the implantable pacemaker cardioverter defibrillator: a comparison of epicardial and endocardial lead systems. Circulation 1995; 92:59-65. 2. Stambler BS, Wood MA, Damiano RJ. Sensing/pacing lead complications with a newer generation implantable cardioverter defibrillator: World wide experience the Guardian ATP 4210 clinical trial. J AM Coll Cardiol; 23:123-32. 3. Bardy GH, Johnson G, Poole JE, et al. A simplified, single lead unipolar transvenous cardioversion-defibrillation system. Circulation 1993; 88: 543-547. 4. Bardy GH, Yee R, Jung W. for the active can investigators. Multicenter experience with a pectoral unipolar implantable cardioverter defibrillator. J Am Coll Cardiol 1996; 28: 400-410. 5. The Antiarrhythmic Versus Implantable Defibrillator (AVID) investigators. A comparison of anti arrhythmic drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias. N Eng J Med 1997; 337:1576-1583. 6. Gradatus R, Block M, Brachmann J , et al. Mortality, Morbidity and complications in 3334 patients with implantable cardioverter- defibrillators. PACE 2003; 26: 1511-1518. 7. Kron J, Herre J, Renfroe EG, et al. Lead and device-related complications in the Antiarrhythmics Versus Implantable Defibrillators Trial. Am Heart J 2001; 141:92-8. 8. Connolly SJ, Gent M, Roberts RS, et al., for the CIDS investigators. Canadian Implantable Defibrillator Study (CIDS): A randomized trial of implantable cardioverter defibrillator against Amiodarone. Circulation 2000; 101:1297-1302. 9. Gold MR, Peters RW, Johnson JW, et al. Complications associated with pectoral implantation of Cardioverter Defibrillators. PACE 1997; 20: 208-211. 10. Witte J, Bondke HJ. The incidence of pacemaker pocket complications depending on pulse generator size and shape- conclusion for defibrillator therapy. PACE 1995; 18:1793. 11. Grimm W, Menz N, Hoffmann J. Complications of third generation implantable cardioverter defibrillator therapy. PACE 1999; 22: 206-11. 12. Rosenqvist M, Beyer T, Block M, European 7219 Jewel ICD investigators. Adverse events with transvenous implantable cardioverter- defibrillators: a prospective multicenter study. Circulation 1998; 98:663-70. 13. Nunain SO, Roelke M; Trouton T. Limitations and late complications of third generation automatic cardioverter- defibrillators. Circulation 1995; 19: 2204-13. 14. Pacifico A, Wheelan KR, Nasir N Jr. Long term follow-up of cardioverter defibrillator implanted under conscious sedation in prepectoral subfacial position. Circulation 1997; 95: 946-950. 15. Brooks R, Garan H, Torchiana D. Three-year outcome of a non-thoracotomy approach to cardioverter defibrillator implantation in 189 consecutive patients. Am J Cardiol 1994; 74: 1011-5. 16. Strickberger SA, Hummel JD, Daoud E. Implantation by electrophysiologists of 100 consecutive cardioverter Defibrillators with nonthoracotomy lead systems. Circulation 1994; 90:868-72. 17. Schwartzman D, Nallamothu N, Callans DJ. Postoperative lead-related complications in patients with nonthoracotomy defibrillation systems. Am J Cardiol 1995; 26:776-86. 18. Kuch KH, Cappata R, Siebels J, et al. Randomized comparison of antiarrhythmic drug therapy with implantable defibrillators in patients resuscitated from cardiac arrest: The Cardiac Arrest Study Hamburg (CASH). Circulation 2000; 102:748-754. 19. Noseworthy PA, Lashevsky I, Dorian P, et al. Feasibility of implantatable Cardioverter Defibrillator use in elderly patients. PACE 2004; 24:373-378. 20. Gupta S, Prevel CD, Shaheen K, et al. Wound complication s and treatment of the infected implantable Cardioverter Defibrillator generator. J Card Surg 1993; 8:671-7. 21. Wunderly RG, Maloney J, Edel T, et al. Infections in implantable Cardioverter Defibrillator patients. PACE 1990; 13: 1360-4. 22. Hauser RG, Kurschinski DT, Mcveigh K, et al. Clinical results with nonthoracotomy ICD systems. PACE 1993; 16: 141-148. 23. Byrd CL. Clinical experience with the extrathoracic introducer insertion technique. PACE 1993; 16:1781-4. 24. Parsonnet V, Roelke M. The cephalic vein cut down versus subclavian puncture for pacemaker/ICD lead implantation. PACE 1999; 22:695-7. 25. Kettering K, Mewis C, Dornberger V, et al. Long term experience with subclavian ICD leads: A comparison among three different types of subclavian leads. PACE 2004; 27: 1355-1361. 26. Glikson M, Lipchenca I, Viskin S, et al. Long term outcome of patients who received implantable cardioverter-defibrillators for stable ventricular tachycardia. J Cardiovasc Electrophysiol, 2004; 15: 658-664. relation_type: [] relation_uri: [] reportno: ~ rev_number: 14 series: ~ source: ~ status_changed: 2007-09-12 17:02:35 subjects: - ipej succeeds: ~ suggestions: ~ sword_depositor: ~ sword_slug: ~ thesistype: ~ title: 'Complications and Mortality of Single Versus Dual Chamber Implantable Cardioverter Defibrillators ' type: journalp userid: 4424 volume: 6