2006-01-21Z2011-03-11T08:56:20Zhttp://cogprints.org/id/eprint/4710This item is in the repository with the URL: http://cogprints.org/id/eprint/47102006-01-21ZDelusional Belief induced by clomiphene treatmentWe report the case of a 35 year old women who developed a complex paranoid delusion during the course of clomiphene treatment für ovulation. The psychopathology was remarkable, because after a short hypomanic period the patient was without severe cognitive disturbance but struggled with a complex monothematic delusion. The delusion vanished in the course of a combination treatment with olanzapine a cognitive behavioral therapy. We could not entirely rule out the possibility of an endogenous psychiatric disease but nevertheless we encountered an unusual monothematic delusion which showed a strong temporal correlation with the intake of clomiphene. We provide some speculation about underlying neurobiological mechanisms on the basis of the dopamine theory of delusion.Dr. Oliver GrimmDr. Petra Hubrich