<> "The repository administrator has not yet configured an RDF license."^^ . <> . . "Short- and long-term experience in pulmonary vein segmental ostial ablation for paroxysmal atrial fibrillation*"^^ . "Introduction: Segmental ostial pulmonary vein isolation (PVI) is considered a potentially curative therapeutic approach in the treatment of paroxysmal atrial fibrillation (PAF). There is only limited data available on the long-term effect of this procedure.\n\nMethods: Patients (Pts) underwent a regular clinical follow up visit at 3, 6 and 24 months after PVI. Clinical success was classified as complete (i.e. no arrhythmia recurrences, no antiarrhythmic drug), partial (i.e. no/only few recurrences, on drug) or as a failure (no benefit). The clinical responder rate (CRR) was determined by combining complete and partial success. \n\nResults: 117 patients (96 male, 21 female), aged 51±11 years (range 25 to 73) underwent a total of 166 procedures (1.4/patient) in 2-4 pulmonary veins (PV). 115 patients (98%) had AF, 2 patients presented with regular PV atrial tachycardia. ,109/115 patients. exhibited PAF as the primary arrhythmia (versus persistent AF). A total of 113 patients with PVI in the years 2001 to 2003 were evaluated for their CRR after 6 (3) months. A single intervention was carried out in 63 patients (55.8%), two interventions were performed in 45 patients (39.8%) and three interventions in 5 patients (4.4%). The clinical response demonstrated a complete success of 52% (59 patients), a partial success of 26% (29 patients) and a failure rate of 22% (25 patients), leading to a CRR of 78% (88 patients). Ostial PVI in all 4 PVs exhibited a tendency towards higher curative success rates (54% versus 44% in patients with 3 PVs ablated for the 6 month follow up). Long-term clinical outcome was evaluated in 39 patients with an ablation attempt at 3 PVs only (excluding the right inferior PV in our early experience) and a mean clinical follow up of 21±6 months. At this point in time the success rate was 41% (complete, 16 patients) and 21% (partial, 8 patients), respectively, adding up to a CRR of 62% (24 patients). In total, 20 patients (17.1%) had either a single or 2 (3 patients, 2.6%) complications independent of the number of procedures performed with PV stenosis as the leading cause (7.7%).\n \nConclusion: The CRR of patients with medical refractory PAF in our patient cohort is 78% at the 6 month follow up. PV stenosis is the main cause for procedure-related complications. Ablation of all 4 PV exhibits a tendency towards higher complete success rates despite equal CRR. Calculation of the clinical response after a mid- to long-term follow of 21±6 months in those patients with an ostial PVI in only 3 pulmonary veins (sparing the right inferior PV) shows a further reduction to 62%, exclusively caused by a drop in patients with a former partial success. To evaluate the long-term clinical benefit of segmental ostial PVI in comparison with other ablation techniques, more extended follow up periods are mandatory, including a larger study cohort and a detailed description of procedural parameters.\n"^^ . "2006-01" . . . "6" . "1" . . "Indian Pacing and Electrophysiology Group"^^ . . . "Indian Pacing and Electrophysiology Journal"^^ . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . "H.J"^^ . "Nesser"^^ . "H.J Nesser"^^ . . "M"^^ . "Martinek"^^ . "M Martinek"^^ . . "J"^^ . "Aichinger"^^ . "J Aichinger"^^ . . "H"^^ . "Pürerfellner"^^ . "H Pürerfellner"^^ . . "Anup"^^ . "Gupta"^^ . "Anup Gupta"^^ . . "Balbir"^^ . "Singh"^^ . "Balbir Singh"^^ . . "Yash"^^ . "Lokhandwala"^^ . "Yash Lokhandwala"^^ . . "J"^^ . "Janssen"^^ . "J Janssen"^^ . . "Johnson"^^ . "Francis"^^ . "Johnson Francis"^^ . . . . . . "Short- and long-term experience in pulmonary vein segmental ostial ablation for paroxysmal atrial fibrillation* (HTML)"^^ . . . . . . "purerfellner3.jpg"^^ . . . "ipej_title.gif"^^ . . . "purerfellner2.jpg"^^ . . . "purerfellner4.jpg"^^ . . . "purerfellner5a.jpg"^^ . . . "ipej_but_editors.gif"^^ . . . "purerfellner.htm"^^ . . . "ipej_but_currentissue.gif"^^ . . . "purerfellnert1.jpg"^^ . . . "purerfellner6.jpg"^^ . . . "ipej_logo_border.gif"^^ . . . "purerfellner1.jpg"^^ . . . "ipej_but_archives.gif"^^ . . . "ipej_but_home.gif"^^ . . . "purerfellner5b.jpg"^^ . . . "Short- and long-term experience in pulmonary vein segmental ostial ablation for paroxysmal atrial fibrillation* (PDF)"^^ . . . . . . . . . "purerfellner.pdf"^^ . . . "Short- and long-term experience in pulmonary vein segmental ostial ablation for paroxysmal atrial fibrillation* (Image (PNG))"^^ . . . . . . "preview.png"^^ . . . "Short- and long-term experience in pulmonary vein segmental ostial ablation for paroxysmal atrial fibrillation* (Indexer Terms)"^^ . . . . . . "indexcodes.txt"^^ . . . "Short- and long-term experience in pulmonary vein segmental ostial ablation for paroxysmal atrial fibrillation* (Indexer Terms)"^^ . . . . . . "indexcodes.txt"^^ . . "HTML Summary of #4672 \n\nShort- and long-term experience in pulmonary vein segmental ostial ablation for paroxysmal atrial fibrillation*\n\n" . "text/html" . . . "Indian Pacing and Electrophysiology Journal" . .