--- abstract: 'Acetylcholine Esterase is an enzyme, which hydrolyses acetylcholine and is used as a marker for cholinergic neural function. It is known to be involved in synaptogenesis. While on one hand it is known to be a marker for the developing chick brain it is also implicated in neurodegenerative diseases. In vertebrates the protein is synthesized by a single gene and undergoes alternative splicing to give 6-8 isoforms. Isozyme patterns of acetylcholine esterase have been suggested to be useful prognostic markers of neuronal degeneration. Lithium a well-known teratogen is known to induce apoptosis in the developing chick brain. Understanding the dynamics of acetylcholine esterase isoform pattern in lithium induced neural tissue damage would help elucidating the role of these isoforms in frank neurodegenerative diseases. We have therefore studied activity and isozyme pattern of acetylcholine esterase in lithium treated and control 7 day old developing chick brain and report the same.' altloc: - http://openmed.nic.in/1183/ - http://anahitagouri.blogspot.com chapter: ~ commentary: ~ commref: ~ confdates: '07 - 10 Jan 2004' conference: 27th All India Cell Biology Conference & International Symposium confloc: 'Pune, India' contact_email: ~ creators_id: - anahita_gouri@hotmail.com - '' - '' - '' creators_name: - family: Gouri given: Anahita honourific: Ms lineage: '' - family: Sathe given: Kinneri honourific: Ms lineage: '' - family: Ramachandran given: Hema honourific: Dr lineage: '' - family: Rajadhyaksha given: Medha honourific: Dr lineage: '' date: 2004 date_type: published datestamp: 2005-12-30 department: ~ dir: disk0/00/00/46/68 edit_lock_since: ~ edit_lock_until: ~ edit_lock_user: ~ editors_id: [] editors_name: [] eprint_status: archive eprintid: 4668 fileinfo: /style/images/fileicons/application_pdf.png;/4668/1/CellBiologyConferencePR.pdf full_text_status: public importid: ~ institution: ~ isbn: ~ ispublished: unpub issn: ~ item_issues_comment: [] item_issues_count: 0 item_issues_description: [] item_issues_id: [] item_issues_reported_by: [] item_issues_resolved_by: [] item_issues_status: [] item_issues_timestamp: [] item_issues_type: [] keywords: 'Anahita Gouri, Acetylcholinesterase, Lithium Chloride, Invertebrate AChE, Vertebrate AChE, developing chick brain' lastmod: 2011-03-11 08:56:14 latitude: ~ longitude: ~ metadata_visibility: show note: "A platform presentation was delivered at the “ Joint International Neuroscience Conference” held in May 2004, at the university of Hyderabad. The author was honoured with the ‘D.M Kar - Young scientist 2004 award’. This project also received the 'Lady Tata Memorial Trust’ scholarship." number: ~ pagerange: ~ pubdom: FALSE publication: ~ publisher: ~ refereed: FALSE referencetext: | 1)Ashwani V. (1992), Ph.D. thesis, University of Mumbai. 2)Ellman G.L., et al. (1961) Biochem. Pharmacol.7,88-95. 3)Krishnan K.S and Manjrekar K. (1987), Annal. Biochem. 160, 409-413. relation_type: [] relation_uri: [] reportno: ~ rev_number: 12 series: ~ source: ~ status_changed: 2007-09-12 17:01:29 subjects: - neuro-chem succeeds: ~ suggestions: The gross morphology picture could be incorporated but will be emailed on request. sword_depositor: ~ sword_slug: ~ thesistype: ~ title: 'Effect of lithium on acetylcholine esterase activity, and isozyme pattern in developing chick brain' type: confposter userid: 6068 volume: ~