?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Rate-Control+or+Rhythm-Contol%3A+Where+do+we+stand%3F%0A&rft.creator=L%2C+Testa&rft.creator=G%2C+Trotta&rft.creator=A%2C+Dello+Russo&rft.creator=M%2C+Casella&rft.creator=G%2C+Pelargonio&rft.creator=F%2C+Andreotti&rft.creator=F%2C+Bellocci&rft.subject=Indian+Pacing+and+Electrophysiology+Journal&rft.description=Atrial+fibrillation+is+the+most+common+sustained+rhythm+disturbance+and+its+prevalence+is+increasing+worldwide+due+to+the+progressive+aging+of+the+population.+Current+guidelines+clearly+depict+the+gold+standard+management+of+acute+symptomatic+atrial+fibrillation+but+the+best-long+term+approach+for+first+or+recurrent+atrial+fibrillation+is+still+debated+with+regard+to+quality+of+life%2C+risk+of+new+hospitalizations%2C+and+possible+disabling+complications%2C+such+as+thromboembolic+stroke%2C+major+bleeds+and+death.+Some+authors+propose+that+regaining+sinus+rhythm+in+all+cases%2C+thus+re-establishing+a+physiologic+cardiac+function+not+requiring+a+prolonged+antithrombotic+therapy%2C+avoids+the+threat+of+intracranial+or+extracranial+haemorrhages+due+to+Vitamin+K+antagonists+or+aspirin.+On+the+contrary%2C+advocates+of+a+rate+control+approach+with+an+accurate+antithrombotic+prophylaxis+propose+that+such+a+strategy+may+avoid+the+risk+of+cardiovascular+and+non+cardiovascular+side+effects+related+to+antiarrhythmic+drugs.+This+review+aims+to+explore+the+state+of+our+knowledge+in+order+to+summarize+evidences+and+issues+that+need+to+be+furthermore+clarified.+%0A&rft.publisher=Indian+Pacing+and+Electrophysiology+Group&rft.contributor=Singh%2C+Balbir&rft.contributor=Lokhandwala%2C+Yash&rft.contributor=Francis%2C+Johnson&rft.contributor=Gupta%2C+Anup&rft.date=2005-10&rft.type=Journal+(Paginated)&rft.type=PeerReviewed&rft.format=text%2Fhtml&rft.identifier=http%3A%2F%2Fcogprints.org%2F4596%2F1%2Ftesta.htm&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F4596%2F2%2Ftesta.pdf&rft.identifier=++L%2C+Testa+and+G%2C+Trotta+and+A%2C+Dello+Russo+and+M%2C+Casella+and+G%2C+Pelargonio+and+F%2C+Andreotti+and+F%2C+Bellocci++(2005)+Rate-Control+or+Rhythm-Contol%3A+Where+do+we+stand%3F++%5BJournal+(Paginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F4596%2F