creators_name: O'Mahony, John F editors_name: Miller, Peter M type: journalp datestamp: 2005-06-19 lastmod: 2011-03-11 08:56:04 metadata_visibility: show title: Cognitive Performance and Liver Function among Recently Abstinent Alcohol Abusers ispublished: pub subjects: neuro-psy subjects: neuro-psych full_text_status: public keywords: Cognitive impairment; liver function; alcohol abuse abstract: It has frequently been suggested that some of the enduring subtle cognitive impairments seen in sober alcohol-dependent persons may be a result of sub-clinical liver dysfunction. Cognitive performance and liver function among 85 recently abstinent alcohol-dependent persons were assessed by means of a neuropsychological examination and the GGT test of liver function. Unlike some previous studies, no relationships were found between the two areas of functioning. It is argued that lack of statistical power did not account for the failure to find an association between the two domains. The proposition that residual cognitive impairment in abstinent alcoholic persons is (partly) mediated by earlier liver dysfunction rests on slight empirical foundations and remains speculative. date: 2005 date_type: published publication: Journal of Addictive Behaviors volume: 30 number: 2 publisher: Elsevier pagerange: 369-373 refereed: TRUE referencetext: Chelune, G.J., & Parker, J. B. (1981). Neuropsychological deficits associated with chronic alcohol abuse. Clinical Psychology Review, 1, 181-195. Cohen, J. (1992). A power primer. Psychological Bulletin, 112, 155-159. Irwin, M., Smith, T. L., Butters, N., Brown, S., Baird, S., Grant, I., & Schuckit, M. A. (1989). Graded neuropsychological impairment and elevated g-glutamyl transferase in chronic alcoholic men. Alcoholism: Clinical and Experimental Research, 13, 99-103. Richardson, E. D., Malloy, P. F., Longabaugh, R., Williams, J., Noel, N., & Beattie, M. C. (1991). Liver function tests and neuropsychological impairment in substance abusers. Addictive Behaviors, 16, 51-55. Russell, E. W. (1988). Renorming Russell’s version of the Wechsler Memory Scale. Journal of Clinical and Experimental Neuropsychology, 40, 235-249. Schafer, K., Butters, N., Smith, T., Irwin, M., Brown, S., Hanger, P., Grant, I., & Schuckit, M. (1991). Cognitive performance of alcoholics: A longitudinal evaluation of the role of drinking history, depression, liver function, nutrition and family history. Alcoholism: Clinical and Experimental Research, 15, 653-660. Stevens, J. (1992). Applied multivariate statistics for the social sciences. (2nd ed.). Hillsdale: NJ, Lawrence Erlbaum Walton, N. H., & Bowden, S. C. (1997). Does liver dysfunction explain neuropsychological status in recently detoxified alcohol-dependent clients? Alcohol and Alcoholism, 32, 287-295. citation: O'Mahony, Dr John F (2005) Cognitive Performance and Liver Function among Recently Abstinent Alcohol Abusers. [Journal (Paginated)] document_url: http://cogprints.org/4387/1/Cognitive_performance_and_liver_function_among_recently_abstinent_alcohol_abusers2005.pdf