title: Brugada Syndrome: The Syndrome of Right Bundle Branch Block, ST segment Elevation in V1 to V3 and Sudden Death creator: Brugada, Josep creator: Brugada, Pedro creator: Brugada, Ramon subject: Indian Pacing and Electrophysiology Journal description: In 1992 a new syndrome consisting of syncopal episodes and/or sudden death in patients with a structurally normal heart and a characteristic electrocardiogram (ECG) with a pattern of right bundle branch block with an ST segment elevation in leads V1 to V3 was described 1 In 1998 the poor prognosis of patients with the syndrome not receiving an implantable defibrillator was reported 2,3 In 1998 the genetic nature of the disease and its assotiation to a mutation in the cardiac sodium channel gene was described 4 . Because the diagnosis is easily made by means of the ECG, an increasing number of patients with the ECG pattern are being identified worldwide. In this article we will review our present knowledge concerning patients with the classical ECG pattern of the disease. publisher: Indian Pacing and Electrophysiology Group contributor: Singh, Balbir contributor: Lokhandwala, Yash contributor: Francis, Johnson contributor: Gupta, Anup date: 2001-10 type: Journal (Paginated) type: PeerReviewed format: text/html identifier: http://cogprints.org/4328/1/brugada.htm identifier: Brugada, Josep and Brugada, Pedro and Brugada, Ramon (2001) Brugada Syndrome: The Syndrome of Right Bundle Branch Block, ST segment Elevation in V1 to V3 and Sudden Death. [Journal (Paginated)] relation: http://cogprints.org/4328/