?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=T+Wave+Alternans+And+Ventricular+Tachyarrhythmia+Risk+Stratification%3A+A+Review&rft.creator=Takagi%2C+Masahiko&rft.creator=Yoshikawa%2C+Junichi&rft.subject=Indian+Pacing+and+Electrophysiology+Journal&rft.description=Sudden+cardiac+death+(SCD)+is+one+of+the+leading+causes+of+mortality+in+industrialized+countries.+Thus%2C+identifying+patients+at+high+risk+of+SCD+is+an+important+goal.+T+wave+alternans+(TWA)+is+a+new+method+for+identifying+patients+with+lethal+ventricular+tachyarrhythmias%2C+and+is+dependent+on+heart+rate.+The+maximal+predictive+accuracy+is+achieved+at+heart+rates+between+100+and+120+bpm%2C+so+that+TWA+is+usually+measured+during+exercise%2C+phamacological+stress%2C+or+atrial+pacing.+It+has+been+shown+that+TWA+has+high+sensitivity+and+negative+predictive+value+for+predicting+SCD+after+myocardial+infarction+and+is+also+useful+for+predicting+SCD+in+patients+with+nonischemic+cardiomyopathy.+Although+the+implantable+cardioverter+defibrillator+(ICD)+is+now+the+primary+therapy+for+preventing+SCD%2C+it+is+difficult+to+identify+those+patients+who+are+susceptible+to+lethal+ventricular+tachyarrhythmias+for+primary+prevention.+In+the+prediction+of+SCD%2C+TWA+can+be+used+as+a+screening+test+of+appropriate+patients+for+further+electrophysiological+examination+and+therapy.%0A&rft.publisher=Indian+Pacing+and+Electrophysiology+Group&rft.contributor=Singh%2C+Balbir&rft.contributor=Lokhandwala%2C+Yash&rft.contributor=Francis%2C+Johnson&rft.contributor=Gupta%2C+Anup&rft.date=2003-04&rft.type=Journal+(Paginated)&rft.type=PeerReviewed&rft.format=text%2Fhtml&rft.identifier=http%3A%2F%2Fcogprints.org%2F4286%2F1%2Ftakagi.htm&rft.identifier=++Takagi%2C+Masahiko+and+Yoshikawa%2C+Junichi++(2003)+T+Wave+Alternans+And+Ventricular+Tachyarrhythmia+Risk+Stratification%3A+A+Review.++%5BJournal+(Paginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F4286%2F