?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Cardiac+Resynchroniztion+Therapy+In+Heart+Failure%3A+Recent+Advances+And+New+Insights&rft.creator=Bhatia%2C+V&rft.creator=Bhatia%2C+R&rft.creator=Dhindsa%2C+S&rft.creator=Virk%2C+A&rft.subject=Indian+Pacing+and+Electrophysiology+Journal&rft.description=Newer+non-pharmacological+therapies+for+heart+failure+are+being+evaluated+for+patients+of+congestive+heart+failure+(CHF).+Mechanical+support+with+left+ventricular+assist+devices+and+heart+transplantation+are+reserved+for+the+minority+of+patients+who+have+severely+decompensated+heart+failure1.+Despite+these+therapeutic+advances%2C+it+is+generally+accepted+that+current+therapies+do+not+adequately+address+the+clinical+need+of+patients+with+heart+failure%2C+and+additional+strategies+are+being+developed.+Cardiac+resynchronization+therapy+(CRT)+is+a+new+modality+that+involves+synchronization+of+ventricular+contraction+and+has+shown+a+lot+of+promise+in+managing+symptomatic+patients+of+CHF+who+are+on+optimal+medical+therapy+and+have+interventricular+conduction+delay+(IVCD).+It+has+improved+exercise+tolerance+and+NYHA+functional+class+in+such+patients+in+sinus+rhythm+and+a+recent+meta-analysis+has+also+shown+mortality+benefits+in+CHF.+Recently+benefits+of+CRT+have+also+been+observed+in+CHF+patients+who+do+not+have+wide+QRS+complexes+on+electrocardiogram+(EKG).+It+has+also+been+shown+to+benefit+drug+refractory+angina+in+CHF.+Recent+studies+have+also+focused+on+the+combined+use+of+CRT+and+implantable+cardioverter+defibrillator+(ICD)+and+it+has+shown+encouraging+results.+Our+aim+in+this+descriptive+review+is+to+define+practice+guidelines+and+to+improve+clinicians'+knowledge+of+the+available+published+clinical+evidence%2C+concentrating+on+few+randomized+controlled+trials.+++++++++&rft.publisher=Indian+Pacing+and+Electrophysiology+Group&rft.contributor=Singh%2C+Balbir&rft.contributor=Lokhandwala%2C+Yash&rft.contributor=Francis%2C+Johnson&rft.contributor=Gupta%2C+Anup&rft.date=2003-07&rft.type=Journal+(Paginated)&rft.type=PeerReviewed&rft.format=text%2Fhtml&rft.identifier=http%3A%2F%2Fcogprints.org%2F4277%2F1%2Fbhatia.htm&rft.identifier=++Bhatia%2C+V+and+Bhatia%2C+R+and+Dhindsa%2C+S+and+Virk%2C+A++(2003)+Cardiac+Resynchroniztion+Therapy+In+Heart+Failure%3A+Recent+Advances+And+New+Insights.++%5BJournal+(Paginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F4277%2F