?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Congenital+Short+QT+Syndrome%0A%0A%0A&rft.creator=Antzelevitch%2C+Charles&rft.creator=Francis%2C+Johnson&rft.subject=Indian+Pacing+and+Electrophysiology+Journal&rft.description=Long+QT+intervals+in+the+ECG+have+long+been+associated+with+sudden+cardiac+death.+The+congenital+long+QT+syndrome+was+first+described+in+individuals+with+structurally+normal+hearts+in+1957.1+Little+was+known+about+the+significance+of+a+short+QT+interval.+In+1993%2C+after+analyzing+6693+consecutive+Holter+recordings+Algra+et+al+concluded+that+an+increased+risk+of+sudden+death+was+present+not+only+in+patients+with+long+QT+interval%2C+but+also+in+patients+with+short+QT+interval+(%3C400+ms).2+Because+this+was+a+retrospective+analysis%2C+further+evaluation+of+the+data+was+not+possible.+It+was+not+until+2000+that+a+short-QT+syndrome+(SQTS)+was+proposed+as+a+new+inherited+clinical+syndrome+by+Gussak+et+al.3+The+initial+report+was+of+two+siblings+and+their+mother+all+of+whom+displayed+persistently+short+QT+interval.+The+youngest+was+a+17+year+old+female+presenting+with+several+episodes+of+paroxysmal+atrial+fibrillation+requiring+electrical+cardioversion.3+Her+QT+interval+measured+280+msec+at+a+heart+rate+of+69.+Her+21+year+old+brother+displayed+a+QT+interval+of+272+msec+at+a+heart+rate+of+58%2C+whereas+the+51+year+old+mother+showed+a+QT+of+260+msec+at+a+heart+rate+of+74.+The+authors+also+noted+similar+ECG+findings+in+another+unrelated+37+year+old+patient+associated+with+sudden+cardiac+death.+&rft.publisher=Indian+Pacing+and+Electrophysiology+Group&rft.contributor=Singh%2C+Balbir&rft.contributor=Lokhandwala%2C+Yash&rft.contributor=Francis%2C+Johnson&rft.contributor=Gupta%2C+Anup&rft.date=2004-04&rft.type=Journal+(Paginated)&rft.type=PeerReviewed&rft.format=text%2Fhtml&rft.identifier=http%3A%2F%2Fcogprints.org%2F4198%2F1%2Fantzelevitch.htm&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F4198%2F2%2Fantzelevitch.pdf&rft.identifier=++Antzelevitch%2C+Charles+and+Francis%2C+Johnson++(2004)+Congenital+Short+QT+Syndrome.++%5BJournal+(Paginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F4198%2F