TY  - GEN
N1  - English translation reprinted with permission from Steinkopff-Springer: Malberg H, Bauernschmitt R, Meyerfeldt U, Schirdewan  A Wessel N. Kurzzeit-Analyse der Herzfrequenzturbulenz versus Variabilitätsparameter und Barorezeptorsensitivität bei Patienten mit dilatativer Kardiomyopathie (Short-term heart rate turbulence analysis versus variability and baroreceptor sensitivity in patients with dilated  cardiomyopathy) Z Kardiol 92:547?557 (2003) (German Journal of Cardiology). 

ID  - cogprints4180
UR  - http://cogprints.org/4180/
A1  - Malberg, Hagen
A1  - Bauernschmitt, Robert
A1  - Meyerfeldt, Udo
A1  - Schirdewan, Alexander
A1  - Wessel, Niels
Y1  - 2004/10//
N2  - New methods for the analysis of arrhythmias and their hemodynamic consequences have been applied in risk stratification, in particular to patients after myocardial infarction. This study investigates the suitability of short-term heart rate turbulence (HRT) analysis in comparison to heart rate and blood pressure variability as well as baroreceptor sensitivity analyses to characterise the regulatory differences between patients with dilated cardiomyopathy (DCM) and healthy controls. In this study, 30 minutes data of non-invasive continuous blood pressure and ECGs of 37 DCM patients and 167 controls measured under standard resting conditions were analysed. The results show highly significant differences between DCM patients and controls in heart rate and blood pressure variability as well as in baroreceptor sensitivity parameters. Applying a combined heart rate-blood pressure trigger, ventricular premature beats were detected in 24.3% (9) of the DCM patients and 11.3% (19) of the controls. This fact demonstrates the limited applicability of short-term HRT analyses. However, the HRT parameters showed significant differences in this subgroup with ventricular premature beats (turbulence onset: DCM: 1.80±2.72, controls: - 4.34±3.10, p<0.001; turbulence slope: DCM: 6.75±5.50, controls: 21.30±17.72, p=0.021). Considering all (including HRT) parameters in the subgroup with ventricular beats, a discrimination rate between DCM patients and controls of 88.0% was obtained (max. 6 parameters). The corresponding value obtained for the total group was 86.3% (without HRT parameters). Comparable classification rates and high correlations between heart rate turbulence and variability and baroreflex parameters point to a more universal applicability of the latter methods.

PB  - Indian Pacing and Electrophysiology Group
KW  - Spontaneous Baroreflex
KW  -  Heart Rate Turbulence
KW  -  Heart Rate Variability
KW  -  Blood Pressure Variability
KW  -  Dilated Cardiomyopathy 
TI  - Short-term Heart Rate Turbulence Analysis Versus Variability and Baroreceptor Sensitivity in Patients With Dilated Cardiomyopathy

SP  - 162
AV  - public
EP  - 175
ER  -

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