creators_name: Collinson, SL creators_name: Phillips, TJ creators_name: James, AC creators_name: Quested, DJ creators_name: Crow, TJ type: journalp datestamp: 2005-01-12 lastmod: 2011-03-11 08:55:49 metadata_visibility: show title: Is lateral bias anomalous in early-onset schizophrenia? Selected comparisons with normal populations ispublished: pub subjects: comp-neuro-sci full_text_status: public keywords: Laterality; Schizophrenia; Handedness; Eye preference; Foot preference abstract: The aim of this study was to investigate lateral bias in patients with early-onset schizophrenia. Hand, eye, and foot preferences and relative hand skill were examined in early-onset patients (n=44) and matched controls (n=39), and were compared with population estimates. Patients demonstrated a significant excess in mixed handedness (20.5% vs. 8.5%) relative to population estimates and reduced relative hand skill on a pegboard task compared with controls. Left eye preference was significantly less common in schizophrenic patients relative to population estimates. Crossed eye-hand and eye-foot preferences were not significantly increased in the patient group as a whole but were present, respectively, in four of nine and five of nine mixed-handed patients but in none of five mixed-handed controls. These findings are consistent with the view that lateralisation is anomalous in schizophrenia early in the course of illness. date: 2004 date_type: published publication: Psychiatry Research volume: 125 publisher: Elsevier Ireland Ltd. pagerange: 219-224 refereed: TRUE referencetext: American Psychiatric Association, 1994. Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), Author, Washington DC. Annett, M., 1970. A classification of hand preference by association analysis. British Journal of Psychology 61, pp. 303–321. Abstract-MEDLINE | Abstract-PsycINFO Boklage, C.E., 1977. 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[Journal (Paginated)] document_url: http://cogprints.org/4033/1/Collinsonsdarticle.pdf