--- abstract: | Background Meta-analyses of hippocampal size have indicated thatthis structure is smaller in schizophrenia.This could reflect a reductioninthe size of constituent neurons or a reduced number of neurons. Aims To measure the size of hippocampalpyramidalneuronsinthe hippocampalpyramidalneurons inthe brains of peoplewith andwithout schizophrenia. Method Pyramidalneuron size in hippocampal subfieldswas estimated stereologically fromsections taken at 5mmintervals throughoutthewhole length of right and left hippocampi from andleft the brains of13 peoplewith schizophrenia and16 controls.Resultswere assessed using repeated-measures analysis of covariance looking for amain effectof diagnosis and gender, andinteractions of and interactions thesewith side. Results Wewere unable to detect significantdifferences related to diagnosis, gender or side for any hippocampal subfield for this series of cases. Conclusions For this series of brains, hippocampal cell size is unchangedin schizophrenia. altloc: [] chapter: ~ commentary: ~ commref: ~ confdates: ~ conference: ~ confloc: ~ contact_email: ~ creators_id: [] creators_name: - family: Highley given: JR honourific: Dr lineage: '' - family: Walker given: M honourific: Ms lineage: '' - family: McDonald given: B honourific: Dr lineage: '' - family: Crow given: TJ honourific: Prof lineage: '' - family: Esiri given: MM honourific: Prof lineage: '' date: 2003 date_type: published datestamp: 2004-12-04 department: ~ dir: disk0/00/00/38/71 edit_lock_since: ~ edit_lock_until: ~ edit_lock_user: ~ editors_id: [] editors_name: [] eprint_status: archive eprintid: 3871 fileinfo: /style/images/fileicons/application_pdf.png;/3871/1/414Highley.pdf full_text_status: public importid: ~ institution: ~ isbn: ~ ispublished: pub issn: ~ item_issues_comment: [] item_issues_count: 0 item_issues_description: [] item_issues_id: [] item_issues_reported_by: [] item_issues_resolved_by: [] item_issues_status: [] item_issues_timestamp: [] item_issues_type: [] keywords: ~ lastmod: 2011-03-11 08:55:42 latitude: ~ longitude: ~ metadata_visibility: show note: ~ number: ~ pagerange: 414-417 pubdom: TRUE publication: British Journal of Psychiatry publisher: Wiley refereed: TRUE referencetext: |+2 Altshuler, L. 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