TY - GEN ID - cogprints33 UR - http://cogprints.org/33/ A1 - Crusio, Wim E. Y1 - 1993/// N2 - The genetic-correlational approach provides a very powerful tool for the analysis of causal relationships between phenotypes. It appears to be particularly appropriate for investigating the functional organization of behavior and/or of causal relationships between brain and behavior. A method for the bivariate analysis of diallel crosses that permits the estimation of correlations due to environmental effects, additive-genetic effects, and/or dominance deviations is described, together with a worked-out example stemming from a five times replicated 4 x 4 diallel cross between inbred mouse strains. The phenotypes chosen to illustrate the analysis were locomotor activity and rearing frequency in an open field. Large, positive additive-genetic and dominance correlations between these two phenotypes were obtained. This finding was replicated in another, independently-executed, diallel cross. KW - diallel cross KW - genetic correlations KW - multivariate analysis KW - brain-behavior relationships KW - neurobehavioral genetics KW - exploratory activity KW - mouse TI - Bi- and Multivariate Analyses of Diallel Crosses: A Tool for the Genetic Dissection of Neurobehavioral Phenotypes SP - 59 AV - public EP - 67 ER -