?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Bi-+and+Multivariate+Analyses+of+Diallel+Crosses%3A+A+Tool+for+the+Genetic+Dissection+of+Neurobehavioral+Phenotypes&rft.creator=Crusio%2C+Wim+E.&rft.subject=Behavioral+Neuroscience&rft.description=The+genetic-correlational+approach+provides+a+very+powerful+tool+for+the+analysis+of+causal+relationships+between+phenotypes.+It+appears+to+be+particularly+appropriate+for+investigating+the+functional+organization+of+behavior+and%2For+of+causal+relationships+between+brain+and+behavior.+A+method+for+the+bivariate+analysis+of+diallel+crosses+that+permits+the+estimation+of+correlations+due+to+environmental+effects%2C+additive-genetic+effects%2C+and%2For+dominance+deviations+is+described%2C+together+with+a+worked-out+example+stemming+from+a+five+times+replicated+4+x+4+diallel+cross+between+inbred+mouse+strains.+The+phenotypes+chosen+to+illustrate+the+analysis+were+locomotor+activity+and+rearing+frequency+in+an+open+field.+Large%2C+positive+additive-genetic+and+dominance+correlations+between+these+two+phenotypes+were+obtained.+This+finding+was+replicated+in+another%2C+independently-executed%2C+diallel+cross.&rft.date=1993&rft.type=Journal+(Paginated)&rft.type=PeerReviewed&rft.format=text%2Fhtml&rft.identifier=http%3A%2F%2Fcogprints.org%2F33%2F1%2Fdiallel2.htm&rft.identifier=++Crusio%2C+Wim+E.++(1993)+Bi-+and+Multivariate+Analyses+of+Diallel+Crosses%3A+A+Tool+for+the+Genetic+Dissection+of+Neurobehavioral+Phenotypes.++%5BJournal+(Paginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F33%2F