?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Toward+Cultural+Oncology%3A+The+Evolutionary+Information+Dynamics+of+Cancer&rft.creator=Wallace%2C+Rodrick&rft.creator=Wallace%2C+Deborah&rft.creator=Wallace%2C+Robert+G.&rft.subject=Theoretical+Biology&rft.description='Racial'+disparities+among+cancers%2C+particularly+of+the+breast+and+prostate%2C+are+something+of+a+mystery.++For+the+US%2C+in+the+face+of+slavery+and+its+sequelae%2C+centuries+of+interbreeding+have+greatly+leavened+genetic+differences+between+'Blacks'+and+'whites'%2C+but+marked+contrasts+in+disease+prevalence+and+progression+persist.++'Adjustment'+for+socioeconomic+status+and+lifestyle%2C+while+statistically+accounting+for+much+of+the+variance+in+breast+cancer%2C+only+begs+the+question+of+ultimate+causality.++Here+we+propose+a+more+basic+biological+explanation+that+extends+the+theory+of+immune+cognition+to+include+elaborate+tumor+control+mechanisms+constituting+the+principal+selection+pressure+acting+on+pathologically+mutating+cell+clones.++The+interplay+between+them+occurs+in+the+context+of+an+embedding%2C+highly+structured%2C+system+of+culturally+specific+psychosocial+stress+which+we+find+is+able+to+literally+write+an+image+of+itself+onto+disease+progression.+The+dynamics+are+analogous+to+punctuated+equilibrium+in+simple+evolutionary+process&rft.date=2003-01&rft.type=Preprint&rft.type=NonPeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F2702%2F1%2Fcancer12.pdf&rft.identifier=++Wallace%2C+Rodrick+and+Wallace%2C+Deborah+and+Wallace%2C+Robert+G.++(2003)+Toward+Cultural+Oncology%3A+The+Evolutionary+Information+Dynamics+of+Cancer.++%5BPreprint%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F2702%2F