--- abstract: "Double spikes during otherwise rhythmic discharge were frequently observed in 'fast' pyramidal tract neurons in response to steady depolarizing currents injected through the recording micropipette. The extra spike appears to arise from a large depolarizing afterpotential crossing the falling threshold several milliseconds following a spike; extra spikes themselves may generate further extra spikes in a similar manner, generating burst patterns which are strikingly similar to those of epileptic neurons." altloc: - http://williamcalvin.com/1970s/1975BrainRes.htm chapter: ~ commentary: ~ commref: ~ confdates: ~ conference: ~ confloc: ~ contact_email: ~ creators_id: [] creators_name: - family: Calvin given: William H. honourific: '' lineage: '' - family: Sypert given: George W. honourific: '' lineage: '' date: 1975 date_type: published datestamp: 1998-04-25 department: ~ dir: disk0/00/00/00/19 edit_lock_since: ~ edit_lock_until: ~ edit_lock_user: ~ editors_id: [] editors_name: [] eprint_status: archive eprintid: 19 fileinfo: /style/images/fileicons/text_html.png;/19/1/1975BrainRes.htm full_text_status: public importid: ~ institution: ~ isbn: ~ ispublished: pub issn: ~ item_issues_comment: [] item_issues_count: 0 item_issues_description: [] item_issues_id: [] item_issues_reported_by: [] item_issues_resolved_by: [] item_issues_status: [] item_issues_timestamp: [] item_issues_type: [] keywords: ~ lastmod: 2011-03-11 08:53:37 latitude: ~ longitude: ~ metadata_visibility: show note: ~ number: ~ pagerange: 498-503 pubdom: FALSE publication: Brain Research publisher: ~ refereed: TRUE referencetext: ~ relation_type: [] relation_uri: [] reportno: ~ rev_number: 8 series: ~ source: ~ status_changed: 2007-09-12 16:21:49 subjects: - neuro-neu succeeds: ~ suggestions: ~ sword_depositor: ~ sword_slug: ~ thesistype: ~ title: 'Cerebral cortex neurons with extra spikes: a normal substrate for epileptic discharges?' type: journalp userid: 23 volume: 83