?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Intraneuronal+information+processing%2C+directional+selectivity+and+memory+for+spatio-temporal+sequences.&rft.creator=Barlow%2C+Horace&rft.subject=Neural+Modelling&rft.description=Interacting+intracellular+signalling+pathways+can+perform+computations+on+a+scale+that+is+slower%2C+but+more+fine-grained%2C+than+the+interactions+between+neurons+upon+which+we+normally+build+our+computational+models+of+the+brain+(Bray+D+1995+Nature+376+307-12).++What+computations+might+these+potentially+powerful+intraneuronal+mechanisms+be+performing%3F+The+answer+suggested+here++is%3A+storage+of+spatio-temporal+trajectories%3B+thus%2C+neurons+have+some+of+the+capacities+required+to+perform+such+a+task.+In+the+retina%2C+it+is+suggested+that+calcium-induced+calcium+release+(CICR)+may+provide+the+basis+for+directional+selectivity.+In+the+cortex%2C+if+activation+mechanisms+with+different+delays+could+be+separately+reinforced+at+individual+synapses+then+each+such+Hebbian+super-synapse+would+store+a+memory+trace+of+the+delay+between+pre-+and+post-synaptic+activity%2C+forming+an+ideal+basis+for+the+memory+and+response+to+phase+sequences.+&rft.date=1996&rft.type=Journal+(Paginated)&rft.type=NonPeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Fcogprints.org%2F1814%2F3%2Fbarlow%25281996%2529.pdf&rft.identifier=++Barlow%2C+Horace++(1996)+Intraneuronal+information+processing%2C+directional+selectivity+and+memory+for+spatio-temporal+sequences.++%5BJournal+(Paginated)%5D+++++&rft.relation=http%3A%2F%2Fcogprints.org%2F1814%2F