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Successful Pregnancy Outcome In Maternal Crigler Najjar Syndrome Type II.

Shakuntala, PN and Poornima, M and Padmalatha, VV and Rao, SR (2012) Successful Pregnancy Outcome In Maternal Crigler Najjar Syndrome Type II. [Journal (On-line/Unpaginated)]

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Abstract

Estimated incidence of Crigler-Najjar syndrome(CNS) is 1 case per 1,000,000 births(1 million). The overall prevalence of CN syndrome is unknown, with only several hundred people reported to have this disease. It is interestingly very rare to encounter a pregnant adult women with congenital jaundice. Pregnancy in CN type II patients is a diagnostic and a therapeutic challenge because of the high risk of bilirubin encephalopathy with serious neurological damage as life-threatening complications for the fetus. To date 8 pregnancy outcome have been reported from 5 women and we report the6 woman with a successful 9 th pregnancy outcome. We have discussed detail history, presentation and management during pregnancy and care of the new born.

Item Type:Journal (On-line/Unpaginated)
Keywords:Crigler Najjer Syndrome type II; Unconjugated hyperbilurubinemia; Phenobarbitone; Phototherapy.
Subjects:JOURNALS > Online Journal of Health and Allied Sciences
ID Code:8922
Deposited By: Kakkilaya Bevinje, Dr. Srinivas
Deposited On:04 May 2013 23:08
Last Modified:04 May 2013 23:08

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