Cogprints

About A Rare Cause Of Primary Hyperparathyroidism

Mona Mlika, Zidi-Moaffak Y , Lakhoua Y, Farah F, Kourda N, Ben Abdallah N, Zermani R, Baltagi-Ben Jilani S , Int J Cur Bio Med Sci. (2011) About A Rare Cause Of Primary Hyperparathyroidism. [Journal (Paginated)]

Full text available as:

[img]
Preview
PDF (About A Rare Cause Of Primary Hyperparathyroidism) - Published Version
Available under License Creative Commons Attribution No Derivatives.

616Kb

Abstract

Introduction: Primary hyperparathyroïdism is observed in 35 to 44 subjects/ 100000 persons. The increased production of parathyroid hormones is secondary to primary glandular modifications consisting mainly in adenomas. The authors report a clear-cell hyperplasia causing primary hyperparathyroidism. Observation: We report the case of a 25-year-old man who was admitted to explore pathologic fractures of the left arm and a malignant hypercalcaemia. Complementary laboratory tests revealed primary hyperparathyroidism. A multiple endocrine neoplasia was excluded by radiologic examinations. Cervical ultra-sound examination revealed 2 parathyroid adenomas and per-operative exploration showed 3 « adenomas ». Microscopic examination of the 4 parathyroid glands specimen concluded to a clear cell hyperplasia. Conclusion: Clear cell hyperplasia is a benign cause of primary hyperparathyroidism. The diagnosis is based upon histologic findings and examination of the 4 glands.

Item Type:Journal (Paginated)
Keywords:Clear cell hyperplasia, hyperparathyroidism, management
Subjects:JOURNALS
ID Code:7322
Deposited By: CurrentSciDirect Publications, International Journal of Current Biological and Medical Science (IJCBMS)
Deposited On:02 May 2011 15:52
Last Modified:02 May 2011 15:52

References in Article

Select the SEEK icon to attempt to find the referenced article. If it does not appear to be in cogprints you will be forwarded to the paracite service. Poorly formated references will probably not work.

[1] Delellis A. Atlas of tumor pathology. Tumors of parathyroid gland. Washington DC: Armed Forces Institute of Pathology, 1993.

[2] Bégueret H, Belleannée G, Dubrez J, Trouette H, Parrens M, Velly JF et al. Clear cell parathyroid adenoma : A rare and challenging lesion. Ann Pathol. 1999 ;19(4) :316-319.

[3] Middleton LP, Merino MJ. The parathyroid glands. In: X. Head and Neck Surgical Pathology. Philadelphia: Lippincott Williams and Wilkins, 2001.

[4] Lawrence DA. A histological comparison of adenomatous and hyperplastic parathyroid glands. J Clin Pathol.. 1978; 31:626-632.

[5] Persson S, Hansson G, Hedman I, Tisell LE, Widéehn S. Primary parathyroid hyperplasia of water-clear cell type. Transformation of water-clear cells into chief cells. Acta Pathol Microbiol Immunol Scand. 1986; 94(6):391-395.

Metadata

Repository Staff Only: item control page