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About A Rare Cause Of Primary Hyperparathyroidism

Mona Mlika, Zidi-Moaffak Y , Lakhoua Y, Farah F, Kourda N, Ben Abdallah N, Zermani R, Baltagi-Ben Jilani S , Int J Cur Bio Med Sci. (2011) About A Rare Cause Of Primary Hyperparathyroidism. [Journal (Paginated)]

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Abstract

Introduction: Primary hyperparathyroïdism is observed in 35 to 44 subjects/ 100000 persons. The increased production of parathyroid hormones is secondary to primary glandular modifications consisting mainly in adenomas. The authors report a clear-cell hyperplasia causing primary hyperparathyroidism. Observation: We report the case of a 25-year-old man who was admitted to explore pathologic fractures of the left arm and a malignant hypercalcaemia. Complementary laboratory tests revealed primary hyperparathyroidism. A multiple endocrine neoplasia was excluded by radiologic examinations. Cervical ultra-sound examination revealed 2 parathyroid adenomas and per-operative exploration showed 3 « adenomas ». Microscopic examination of the 4 parathyroid glands specimen concluded to a clear cell hyperplasia. Conclusion: Clear cell hyperplasia is a benign cause of primary hyperparathyroidism. The diagnosis is based upon histologic findings and examination of the 4 glands.

Item Type:Journal (Paginated)
Keywords:Clear cell hyperplasia, hyperparathyroidism, management
Subjects:JOURNALS
ID Code:7322
Deposited By:CurrentSciDirect Publications, International Journal of Current Biological and Medical Science (IJCBMS)
Deposited On:02 May 2011 16:52
Last Modified:02 May 2011 16:52

References in Article

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[1] Delellis A. Atlas of tumor pathology. Tumors of parathyroid gland. Washington DC: Armed Forces Institute of Pathology, 1993.

[2] Bégueret H, Belleannée G, Dubrez J, Trouette H, Parrens M, Velly JF et al. Clear cell parathyroid adenoma : A rare and challenging lesion. Ann Pathol. 1999 ;19(4) :316-319.

[3] Middleton LP, Merino MJ. The parathyroid glands. In: X. Head and Neck Surgical Pathology. Philadelphia: Lippincott Williams and Wilkins, 2001.

[4] Lawrence DA. A histological comparison of adenomatous and hyperplastic parathyroid glands. J Clin Pathol.. 1978; 31:626-632.

[5] Persson S, Hansson G, Hedman I, Tisell LE, Widéehn S. Primary parathyroid hyperplasia of water-clear cell type. Transformation of water-clear cells into chief cells. Acta Pathol Microbiol Immunol Scand. 1986; 94(6):391-395.

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