Cogprints

Metaplastic Carcinoma of the Left Breast with Extensive Chondroid Differentiation

Nikumbh, Dhiraj B and Jagtap, Sunil V and Kanetkar, Sujata R and Jain, Gaurav and Bohra, Ashish (2011) Metaplastic Carcinoma of the Left Breast with Extensive Chondroid Differentiation. [Journal (On-line/Unpaginated)]

Full text available as:

[img]
Preview
PDF - Published Version
Available under License Creative Commons Attribution No Derivatives.

316Kb

Abstract

Metaplastic breast carcinoma is very rare neoplasm which contains mixture of carcinomatous (epithelial) and sarcomatous (mesenchymal) elements in variable proportion. Metaplastic carcinoma with chondroid differentiation is even rarer. We report a case of metaplastic carcinoma with extensive chondroid differentiation as there is paucity of information regarding pathological features and clinical outcomes for these rare tumors. Tumor had characteristic definite areas of classic infiltrating duct carcinoma with abundant chondromyxoid matrix, focal areas of chondrosarcoma and cartilagenous metaplasia. Tumour cells were immunoreactive for S-100, ER, and PR. When pathologist encounter breast tumor with chondroid differentiation, careful gross sampling, histopathology and immunoreactivity for mesenchymal and epithelial component are most useful to differentiate metaplastic carcinoma from malignant phylloides tumors and malignant adenomyoepithelioma.

Item Type:Journal (On-line/Unpaginated)
Keywords:Metaplastic carcinoma; Chondroid differentiation
Subjects:JOURNALS > Online Journal of Health and Allied Sciences
ID Code:7277
Deposited By:Kakkilaya Bevinje, Dr. Srinivas
Deposited On:02 May 2011 18:14
Last Modified:02 May 2011 18:14

References in Article

Select the SEEK icon to attempt to find the referenced article. If it does not appear to be in cogprints you will be forwarded to the paracite service. Poorly formated references will probably not work.

1. Rosen PP. Carcinoma with metaplasia.In :Rosen PP,editor.Rosens Breast Pathology. 2nd edition. Philadelphia: Lippincott Williams and Wilkins. 2001. pp 425-452

2. Tavassoli FA. Papillary lesions.In :Tavassoli FA,editor.Pathology of Breast. 2nd edition. Stanford (CT): Appleton and Lange. 1999. 481-504

3. Dunne B, Lee AH, Pinder SE et al. An immunohitochemical study of metaplastic spindle cell carcinoma, phyllodes tumour and fibromatosis of breast. Hum Pathology 2003;34:1009–1015

4. Pollock JM, Green A, Donnell C, Dyess DL, Tucker JA. Metaplastic Breast Carcinoma with Osseous Differentiation: A Case Report Southern Medical Journal February 2006;99(2):168-170. Available at http://journals.lww.com/smajournalonline/fulltext/2006/02000/metaplastic_breast_carcinoma_with_osseous.19.aspx#

5. Ellios ID, Corneli ssc CJ, Schnitt SJ et al. Tumour of breast. Invasive Breast Carcinoma. In: Tavassoli FA, Devileep, editors. Pathology and Genetics of tumours of breast and female genital organs. Lyon; IARC Press. 2003. pp 37-41

6. Tavassoli FA. Classification of Metaplastic Carcinoma of breast. Pathol Annu 1992;27:89-119.

7. Havos AG, Lucas JC, Forte FW. Metaplastic breast carcinoma: Rare form of mammary cancer. NY State J Med 1973;73:1078-1082.

8. Al Sayed AD, Elweshi AM, Tulba AM et al. Metaplastic carcinoma of the breast clinical presentation treatment result and prognostic factors. Acta Onchologica. 2006;45:188-195

9. Wargotz ES, Norris HJ. Metaplastic carcinoma of the breast. I. Matrix producing carcinoma. Hum Pathol 1989;20:628-635

10. Park JM, Hum BK, Moon WK, et al. Metaplastic Carcinoma of the breast : Mammographic and sonographic findings. J clinical Ultrasound 2000;28:179-186.

11. Gunhan BI, Memis A, Ustam EE et al. Metaplastic carcinoma of breast: Clinical, mammographic and sonographic findings with histological correlation. AJR 2002;178:1421-1425.

12. Patterson SK, Tworek JA, Ranbidoux MA et al. Metaplastic carcinoma of the breast; Mammographic appearance with pathological correlation. AJR 1997;169:709-712

13. Gupta S, Gupta V, Aggarwal PN et al. Primary chondrosarcoma of the breast: A case report. Indian Journal of Cancer 2003;40:77-79

14. Hee JS, Hak HK, Sun MK, et al. Imaging features of metaplastic carcinoma with chondroid differentiation of the breast. AJR 2007;188:691-696

Metadata

Repository Staff Only: item control page