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Eye-contact and complex dynamic systems: an hypothesis on autism’s direct cause and a clinical study addressing prevention.

McDowell, Dr Maxson J. (2010) Eye-contact and complex dynamic systems: an hypothesis on autism’s direct cause and a clinical study addressing prevention. [Journal (On-line/Unpaginated)] (Unpublished)

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Abstract

Estimates of autism’s incidence increased 5-10 fold in ten years, an increase which cannot be genetic. Though many mutations are associated with autism, no mutation seems directly to cause autism. We need to find the direct cause. Complexity science provides a new paradigm - confirmed in biology by extensive hard data. Both the body and the personality are complex dynamic systems which spontaneously self-organize from simple dynamic systems. Autism may therefore be caused by the failure of a simple dynamic system. We know that infants who cannot track their mother’s face often become autistic, that eye-contact initiates intersubjectivity which is blocked in autism, and that the infant-mother pair seems designed to promote eye-contact, as does the eye’s appearance. This author earlier proposed that failure of eye-contact might directly cause autism and that early non-maternal childcare, including television/video, would therefore be statistically linked to autism. Waldman et al. (2008; 2006) recently proved that autism is strongly linked to precipitation (indoor activity) and to the introduction of cable. The most plausible explanation? Early exposure to television/video is linked to autism. Furthermore a normal developmental cascade (blocked in autism) has been deciphered: (a) Infant-mother eye-contact triggers increased maternal attention. (b) Early maternal attention permanently increases not only baseline vasopressin but also that oxytocin release which is triggered by subsequent maternal attention. (c) Vasopressin and oxytocin promote face recognition, gazing-at-the-eyes, emotion recognition, and social bonding. The eye-contact hypothesis suggests a clinical study addressing prevention: recruit prospective parents who agree to curtail television/video/computer/wi-fi in their families; measure autism’s incidence in their children.

Item Type:Journal (On-line/Unpaginated)
Keywords:Autism spectrum disorder; Asperger's syndrome; Complexity; Complex dynamic system; Eye contact; Face recognition; Infant-mother dyad; Intersubjectivity; Oxytocin; Self-organized; Emergent; Early television exposure
Subjects:Neuroscience > Behavioral Neuroscience
Biology > Behavioral Biology
Biology > Theoretical Biology
Psychology > Clinical Psychology
Psychology > Comparative Psychology
Psychology > Developmental Psychology
Philosophy > Philosophy of Mind
Psychology > Psychobiology
ID Code:7168
Deposited By:McDowell, Doctor Maxson J.
Deposited On:11 Jan 2011 03:27
Last Modified:11 Mar 2011 08:57

References in Article

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Abrahams, B. S. & Geschwind, D. H. (2008) Advances in autism genetics: on the threshold of a new neurobiology. Nature Reviews Genetics 9, 341-355.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756414/

Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P. (2007). The Molecular Biology of the Cell, Fifth Edition. New York: Garland Science.

Als, H., Tronic, E. & Brazelton, T. B. (1980). Stages of early behavioral organization: the study of a sighted infant and a blind infant in interaction with their mothers. In: High-Risk Infants and Children, ed. T. M. Field, , 181-204. New York: Academic Press.

American Academy of Pediatrics Committee on Public Education (2001). Policy Statement: Children, Adolescents, and Television. Pediatrics, 107: 423-6. http://aappolicy.aappublications.org/cgi/content/full/pediatrics;107/2/423

Andari, E., Duhamel, J.-R., Zalla, T., Herbrecht, E., Leboyer, M., & Sirigu, A. (2010). Promoting social behavior with oxytocin in high- functioning autism spectrum disorders. Proceedings of the National Academy of Sciences, USA Online, February 16th.

http://www.pnas.org/content/early/2010/02/05/0910249107.full.pdf+html

Anderson, D. R. & Pempek, (2005). T. A., Television and very young children. American Behavioral Scientist, 48: 505-22. http://abs.sagepub.com/content/48/5/505.abstract

Arthur, W. B. (1999). Complexity and the Economy. Science 2, 284 (5411): 107-9.

http://time.dufe.edu.cn/jingjiwencong/waiwenziliao1/econcomplexweb.pdf

Asperger H. (1944). Die ‘autischen Psychopathen’ im Kindesalter. Archiv fur Psychiatrie und Nervenkrankheiten, 17: 76-136.

Auyeung, B., Taylor, K., Hackett, G. & Baron-Cohen, S. (2010). Foetal testosterone and autistic traits in 18 to 24-month-old children. Molecular Autism. 1(11). http://www.molecularautism.com/content/1/1/11

Baron-Cohen S (1994). How to build a baby that can read minds: cognitive mechanisms in mindreading. Cahiers de Psychologie

Cognitive, 13: 513–52.

Baron-Cohen, S., Wheelwright, S. & Jolliffe, T. (1997). Is there a "language of the eyes"? Evidence from normal adults and adults with autism or Asperger syndrome. Visual Cognition, 4(3): 311-31.

Baron-Cohen, S., Wheelwright, S., Skinner, R., Martin, J., & Clubley, E. (2001): The Autism Spectrum Quotient (AQ): evidence from Asperger syndrome/high functioning autism, males and females, scientists and mathematicians. Journal of Autism and Developmental Disorders, 31:5-17. http://www.autismresearchcentre.com/docs/papers/2001_BCetal_AQ.pdf

Baron-Cohen, S. (2003). The Essential Difference: Men, Women and the Extreme Male Brain. Penguin, London.[(null)]

Baron-Cohen, S., Knickmeyer, R. C., & Belmonte, M. K. (2005). Sex differences in the brain: implications for explaining autism. Science. Nov 4., 310(5749): 819-23.

http://www.ncbi.nlm.nih.gov/pubmed/16272115

Beebe, B., Lachman, F. M. & Jaffe, J. (1997). Mother-infant interaction structures and presymbolic self- and object representations. Psychoanalytic Dialogues, 7(2): 133–82.

http://www.pep-web.org/document.php?id=pd.007.0133a

Beebe, B. & Lachmann, F. M. (1998). Co-constructing inner and relational processes: Self and mutual regulation in infant research and adult treatment. Psychoanalytic Psychology, 15 (4): 480-516.

http://nyspi.org/Communication_Sciences/PDF/Infant%20research%20and%20adult%20treatment/BB-co-constructing%20inner%20and%20relational%203.6.07.pdf

Beebe, B. (2005). Mother–infant research informs mother–infant treatment. Psychoanalytic Study of the Child, 60: 7-46. (2010). Clinical Social Work Journal, 38: 17-36.

Bergman, A. (1985). From psychological birth to motherhood: the treatment of an autistic child with follow-up into her adult life as a mother. In: Parental influences in health and disease, eds E. J. Anthony and G. H. Pollock, 91-120. Boston: Little, Brown.

Bion, W. R. (1962/1977). Learning from experience . In: Seven Servants. New York: Jason Aronson.

Broad Institute of MIT and Harvard (2008). Human gene count tumbles again. ScienceDaily. http://www.sciencedaily.com/releases/2008/01/080113161406.htm

Bonabeau, E., Theraulaz, G., Deneubourg, S. A., & Camzine, S. (1997). Self-organization in social insects. Trends in ecology and evolution, 12 (5): 188-93. http://www.biosci.utexas.edu/ib/faculty/mueller/384k/selforganization.PDF

Bower, B. (2009). Joint attention provides clues to autism and cooperation: Different paths to childhood autism. Science News, 176(10): 15. http://www.sciencenews.org/view/generic/id/48055/title/Joint_attention_provides_clues_to_autism_and_cooperation

Brown, R., Hobson, R. P., Lee, A & Stevenson, J. (1997). Are there "autistic like" features in congenitally blind children? Journal of Child Psychology and Psychiatry, 38(6): 693-703. http://www.ncbi.nlm.nih.gov/pubmed/9315979

Byrd, R. (2002). Report to the legislature on the principle findings from "The epidemiology of autism in California: a comprehensive pilot study." http://www.ourstolenfuture.org/NewScience/behavior/2002/2002-10byrd.htm

California Department of Developmental Services (2007). Autism Spectrum Disorders. Changes in the California Caseload An Update: June 1987 – June 2007.

http://www.dds.ca.gov/autism/docs/AutismReport_2007.pdf

Carver, C. S., & Scheier, M. F. (2000). Perspectives on personality (4th ed.), 5. Boston: Allyn and Bacon.

Chakrabarti, B., Dudbridge, F., Kent, L., Wheelwright, S., Hill Cawthorne, G., Allison, C., Banerjee-Basu, S., & Baron-Cohen, S. (2009). Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome. Autism Research 2(3): 157–77. http://www.ncbi.nlm.nih.gov/pubmed/19598235

Chawarska, K., Volkmar, F., & Klin, A. (2010). Limited attentional bias for faces in toddlers with autism spectrum disorders. Archives of General Psychiatry. 67(2):178-85. http://www.ncbi.nlm.nih.gov/pubmed/20124117

Chimpanzee Sequencing and Analysis Consortium (2005). Initial sequence of the chimpanzee genome and comparison with the human genome. Nature, 437: 69-87.

http://www.nature.com/nature/journal/v437/n7055/full/nature04072.html#a25

Christakis, D. A., Zimmerman, F. J., DiGiuseppe, D. L. & McCarthy, C. A. (2004). Early Television Exposure and Subsequent Attentional Problems in Children. Pediatrics, 113: 708-13. http://pediatrics.aappublications.org/cgi/content/full/113/4/708

Christakis, D. A., Gilkerson, J., Richards, J. A., Zimmerman, F. J., Garrison, M. M., Xu, D., Gray, S., Yapanel, U. (2009). Audible television and decreased adult words, infant vocalizations, and conversational turns: a population-based study

Archives of Pediatrics & Adolescent Medicine. 2009;163(6):554-558.

http://archpedi.ama-assn.org/cgi/content/abstract/163/6/554

Christakis, D. A. (2009). The effects of infant media usage: what do we know and what should we learn? Acta Paediatrica 98(1): 8-16.

Christakis, D. A. (2010). Internet addiction: a 21st century epidemic?

BioMed Central Medicine. 2010; 8: 61. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972229/?tool=pubmed

Doheny, K. (2009). Study shows some children may ‘move off’ the autism spectrum. WebMD Health News, May 11th.

http://www.webmd.com/brain/autism/news/20090511/researchers-see-recovery-from-autism

Dunbar, R. I. M. (1992). Neocortex size as a constraint on group size in primates. Journal of Human Evolution, 20: 469-93.

http://www.sciencedirect.com/science/article/B6WJS-4F1J80W-G5/2/2f4bddfc940ff3a4b4be2215e17a0c2e

Elman, J. L., Bates, E. A., Johnson, M. H., Karmiloff-Smit, A., Parisi, D. & Plunkett, K. (1998). Rethinking Innateness: A Connectionist Perspective on Development. Cambridge: MIT Press.

Elsabbagh, M., Volein, A., Csibra, G., Holmboe, K., Garwood, H., Tucker, L., Krljes, S., Baron-Cohen, S., Bolton, P., Charman, T., Baird, G., & Johnson, M. H. (2009). Neural Correlates of Eye Gaze Processing in the Infant Broader Autism Phenotype. Biological Psychiatry, 65: 31-8.

http://www.autismresearchcentre.com/docs/papers/2009_Elsabbagh_etal_BiolPsychiatry.pdf

Emery, N. J. (2000). The eyes have it: the neuroethology, function and evolution of social gaze. Neuroscience and Biobehavioral Reviews, 24: 581-604. http://www.sciencedirect.com/science/article/B6T0J-40XNW1G-1/2/57aa221475c6297b246a8bc1c694230b

Farroni, T., Csibra, G., Simion, F. & Johnson, M. H. (2002). Eye-contact detection in humans from birth. Proceedings of the National Academy of Sciences USA, 99(14): 9602-5. http://www.pnas.org/content/99/14/9602.long ;

Visual stimuli photographs of direct gaze and averted gaze. http://www.pnas.org/content/99/14/9602/F1.large.jpg

Farroni, T., Johnson, M. H., Menon, E., Zulian, L., Faraguna, D., & Csibra, G. (2005). Newborns' preference for face-relevant stimuli: Effects of contrast polarity. Proceedings of the National Academy of Sciences USA, 102(47) 17245-50. http://www.pnas.org/content/102/47/17245.full

Farroni, T., Menon, E., Rigato, S., & Johnson, M. H. (2007). The perception of facial expressions in newborns. European Journal of Developmental Psychology 4(1): 2–13.

http://www.informaworld.com/smpp/content~db=all?content=10.1080/17405620601046832

Friaberg, S. (1977). Insights from the Blind: Comparative Studies of Blind and Sighted Infants. New York: Basic Books.

Freedman, D. (1964). Smiling in infants and the issue of innate vs. acquired. Journal of Child Psychology and Psychiatry, 5: 171-84.

Frith U, ed. (1991). Autism and Asperger Syndrome. Cambridge University Press.

Fries, A. B. W., Ziegler, T. E., Kurian, J. R., Jacoris, S., & Pollak, S. D. (2005). Early experience in humans is associated with changes in neuropeptides critical for regulating social behavior. Proceedings of the National Academy of Sciences USA, 102(47): 17237-40.

http://www.pnas.org/content/102/47/17237.full

Gans, C. & Parsons, T. S. (1973). Biology of the Reptiles, 4, Morphology D, 104. London: Academic Press.

Ganz, M. L., (2006). The costs of autism. In: Understanding Autism: From Basic Neuroscience to Treatment, ed. S.O. Moldin and J.L.R. Rubenstein. New York: CRC Press.

Ganz, M. L., (2007). The lifetime distribution of the incremental societal costs of autism. Archives of Pediatric & Adolescent Medicine. 161(4):343-349.

http://archpedi.ama-assn.org/cgi/content/full/161/4/343#REF-POA60120-1

Gergely, G. (2001). The obscure object of desire: ‘Nearly, but clearly not, like me.’ Contingency preference in normal children versus children with autism. Bulletin of the Menninger Clinic, 65: 411–26. http://web.ceu.hu/phil/gergely/papers/2001_BMC_The_obscure_object_of_desire.pdf

Gergely, G. & Watson, J. S. (1996). The social biofeedback theory of parental affect mirroring. International Journal of Psycho-Analysis, 77: 1181–212. http://web.ceu.hu/phil/gergely/papers/1996_Gergely_Watson_The_social_biofeedback_theory.pdf

Gillberg, C. & Wing, L. (1999). Autism: not an extremely rare disorder. Acta Psychiatrica Scandinavica, 99(6): 399-406. http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0447.1999.tb00984.x/abstract

Grossmann, T., & Johnson, M. H. (2010). Selective prefrontal cortex responses to joint attention in early infancy. Biology Letters 6(4): 540–543.

http://rsbl.royalsocietypublishing.org/content/6/4/540

Guastella, A. J., Einfeld, S. L., Gray, K., M., Rinehart, N., J., Tonge, B., J., Lambert, T., J. & Hickie, I., B. (2010). Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders. Biological Psychiatry, 67 (7).

http://www.biologicalpsychiatryjournal.com/article/S0006-3223(09)01122-6/abstract

Haaf, R. A. & Bell, R. Q. (1967). A facial dimension in visual discrimination by human infants. Child Development, 38: 892-9.

Haith, M. M. (1966). The response of the human newborn to visual movement. Journal of Experimental Child Psychology, 3: 235-43.

Hamermesh, D. S., Frazis, H., & Stewart, J. (2005). Data watch: The American Time Use Survey. Journal of Economic Perspectives, 19: 221-32.

Hobson, R. P., Lee, A. & Brown, R. (1999). Autism and congenital blindness. Journal of Autism and Developmental Disorders, 29(1): 45-56. http://www.ncbi.nlm.nih.gov/pubmed/10097994

Hobson, P. (2002). The Cradle of Thought: Exploring the Origins of Thinking. London: Macmillan.

Holland, J. (1995) Hidden Order: How Adaptation builds Complexity. Reading, MA: Perseus.

Holland, J. (1998). Emergence from chaos to order. Reading, MA: Perseus.

Hormatertz-Picciotto, I. & Delwiche, L. (2009), The rise of autism and the role of age in diagnosis. Epidemiology, 20(1): 84-90. http://www.ncbi.nlm.nih.gov/pubmed/19234401

Jaffe, J., Beebe, B., Feldstein, S., Crown, C. L. & Jasnow, M. D. (2001). Rhythms of dialogue in infancy: coordinated timing in development. Monograph of the Society for Research in Child Development, 66(2): i-viii, 1-132. http://www.ncbi.nlm.nih.gov/pubmed/11428150

James, I. (2003). Singular scientists. Journal of the Royal Society of Medicine. 96(1): 36–9. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC539373/

Janzen, D. H., Hallwachs, W., & Burns, J. M. (2010). A tropical horde of counterfeit predator eyes. Proceedings of the National Academy of Sciences USA, 107(26): 11659-65.

http://pubget.com/paper/20547863

Johnson, M. H. & Morton, J. (1991). Biology and Cognitive Development: The Case of Face Recognition. Oxford: Blackwell.

Kaiser Family Foundation (2003). Zero to six: electronic media in the lives of infants, toddlers, and preschoolers. Kaiser Family Foundation, Menlo Park, CA. http://www.kff.org/entmedia/loader.cfm?url=/commonspot/security/getfile.cfm&PageID=22754

Kaiser Family Foundation (2006) The Media Family: Electronic Media in the Lives of Infants, Toddlers, Preschoolers, and their Parents. Kaiser Family Foundation: Menlo Park, CA. http://www.kff.org/entmedia/upload/7500.pdf

Kaiser, M. D., Hudac, C. M., Shultza, S., Leea, S. M., Cheung, C., Berken, A. M., Deen, B.,Pitskel, N. B., Sugrue, D. R., Voos, A. C., Saulnier, C. A., Ventola, P., Wolf, J. M., Klin, A., Vander Wyk, B. C. & Pelphrey, K. A. (2010). Neural signatures of autism. Proceedings of the National Academy of Sciences, 107(49): 21223-21228. http://www.Pnas.Org/cgi/doi/10.1073/pnas.1010412107

Karmiloff-Smith, A. (2009). Nativism versus neuroconstructivism: rethinking the study of developmental disorders. Developmental Psychology, 45(1): 56-63.

http://www.psyc.bbk.ac.uk/research/DNL/personalpages/aks/Nativism%20vs%20Neuroconstructivism.pdf

Klin, A. & Jones, W. (2007). Embodied psychoanalysis? Or, on the confluence of psychodynamic theory and developmental science. In: Developmental Science and Psychoanalysis: integration and innovation, eds L. Mayes, P. Fonagy and M. Target, Karnac, London, 5-38.

Klin, A. & Jones, W. (2008) Altered face scanning and impaired recognition of biological motion in a 15-month-old infant with autism. Developmental Science 11(1): 40-46. http://www.ingentaconnect.com/content/bpl/desc/2008/00000011/00000001/art00006

Klin, A., Lin, D. J., Gorrindo, P., Ramsay G., & Jones, W. (2009). Two-year-olds with autism orient to non-social contingencies rather than biological motion. Nature letters 459, 14 May.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758571/

Klin, A., Jones, W., Schultz, R., Volkmar, F., & Cohen, D. (2002). Visual fixation patterns during viewing of naturalistic social situations as predictors of social competence in individuals with autism. Archives of General Psychiatry, 59(9): 809-16. http://www.ncbi.nlm.nih.gov/pubmed/12215080

Kogan, M. D., Blumberg, S. J., Schieve, L. A., Boyle, C. A., Perrin, J. M., Ghandour, R. M., Singh, G. K., Strickland, B. B., Trevathan, E., & van Dyck, P. C. (2009) National Children's Health Survey Report: Prevalence of Parent-Reported Diagnosis of Autism Spectrum Disorder Among Children in the US, 2007. Pediatrics, 124(5): 1395-403.

http://pediatrics.aappublications.org/cgi/content/abstract/peds.2009-1522v1

Levin, S. A. (1998). Ecosystems and the biosphere as complex adaptive systems. Ecosystems 1: 431-6.

Loeuille, N. (2009). Evolution of communities an

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